Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRAF | P15056 | 2/20 | 0.40 |
| ▸ | RAF1 | P04049 | 1/20 | 0.40 |
| ▸ | ARAF | P10398 | 1/20 | 0.40 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.40 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | TTPA | P49638 | 2/20 | 0.38 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9075111 | 0.99 | BRAF (0.39) | BRAFRAF1ARAFCYP4F2NR1I2 | |
| SCHEMBL9073519 | 0.96 | MEN1 (0.39) | BRAFRAF1ARAFCYP4F2NR1I2 | |
| Hydrochloric Acid SCHEMBL9075956 | 0.95 | MEN1 (0.39) | BRAFRAF1ARAFCYP4F2NR1I2 | |
| SCHEMBL9074780 | 0.94 | BRAF (0.39) | BRAFRAF1ARAFCYP4F2NR1I2 | |
| SCHEMBL9558659 | 0.93 | CYP4F2 (0.44) | CYP4F2NR1I2ALOX5MAPTMEN1 | |
| Hydrochloric Acid SCHEMBL9224276 | 0.93 | BRAF (0.38) | BRAFRAF1ARAFCYP4F2NR1I2 | |
| Hydrochloric Acid SCHEMBL9075339 | 0.93 | CYP4F2 (0.44) | CYP4F2NR1I2ALOX5MAPTMEN1 | |
| SCHEMBL9074769 | 0.90 | BRAF (0.38) | BRAFRAF1ARAFNR1I2ALOX5 | |
| Hydrochloric Acid SCHEMBL9075209 | 0.89 | BRAF (0.38) | BRAFRAF1ARAFNR1I2ALOX5 | |
| SCHEMBL9073406 | 0.89 | CYP4F2 (0.37) | CYP4F2NR1I2ALOX5MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5508450-A | INHIBITORY EFFECT ON MAILLARD REACTION AND ANTIOXIDIZING EFFECT; TREATS OR PREVENTS DIABETIC COMPLICATIONS | ONO PHARMACEUTICAL CO., LTD. (JP) | 1996-04-16 | — | — | US | claimed |