Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 20/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9075955 | 1.00 | TACR1 (1.00) | TACR1 | |
| SCHEMBL9024814 | 0.88 | TACR1 (0.94) | TACR1 | |
| SCHEMBL9024829 | 0.88 | TACR1 (0.94) | TACR1 | |
| SCHEMBL9024804 | 0.88 | TACR1 (0.94) | TACR1 | |
| SCHEMBL9366823 | 0.87 | TACR1 (1.00) | TACR1 | |
| SCHEMBL9024514 | 0.87 | TACR1 (1.00) | TACR1 | |
| SCHEMBL8539701 | 0.85 | TACR1 (0.73) | TACR1 | |
| SCHEMBL9076046 | 0.83 | TACR1 (0.77) | TACR1 | |
| SCHEMBL9076044 | 0.83 | TACR1 (0.77) | TACR1 | |
| SCHEMBL9544240 | 0.81 | TACR1 (0.77) | TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993021181-A1 | AZACYCLIC COMPOUNDS | MERCK SHARP & DOHME LIMITED (GB) | 1993-10-28 | — | — | WO | claimed |
| US-5496833-A | BRONCHODILATOR, ANTIINFLAMMATORY, ANTIARTHRITIC, ANALGESIC, AND ANTIMIGRAINE AGENTS | MERCK SHARP & DOHME LIMITED (GB) | 1996-03-05 | — | — | US | disclosed |
| US-5444074-A | Treating diseases associated with excess of substance P | MERCK SHARP & DOHME LIMITED (GB) | 1995-08-22 | — | — | US | disclosed |