Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.43 |
| ▸ | CDK4 | P11802 | 2/20 | 0.42 |
| ▸ | CCND1 | P24385 | 2/20 | 0.42 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | ACHE | P22303 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4315585 | 0.80 | TAAR1 (0.50) | TAAR1MAOBADRA2AADRA2BADRA2C | |
| SCHEMBL2712926 | 0.80 | TAAR1 (0.50) | TAAR1MAOBADRA2AADRA2BADRA2C | |
| SCHEMBL256804 | 0.78 | TAAR1 (0.48) | TAAR1MAOBADRA2AADRA2BADRA2C | |
| SCHEMBL1669101 | 0.76 | IDO1 (0.57) | TAAR1MAOB | |
| SCHEMBL5431489 | 0.76 | TAAR1 (0.46) | TAAR1MAOBADRA2AADRA2BADRA2C | |
| Lithium SCHEMBL18580003 | 0.76 | TAAR1 (0.46) | TAAR1MAOBADRA2AADRA2BADRA2C | |
| SCHEMBL608533 | 0.76 | MAOB (0.49) | TAAR1MAOBADRA2AADRA2BADRA2C | |
| SCHEMBL5865486 | 0.76 | TAAR1 (0.46) | TAAR1MAOBADRA2AADRA2BADRA2C | |
| SCHEMBL710879 | 0.76 | TAAR1 (0.46) | TAAR1MAOBADRA2AADRA2BADRA2C | |
| Fluoride SCHEMBL28760317 | 0.76 | TAAR1 (0.46) | TAAR1MAOBADRA2AADRA2BADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8450442-B2 | Borosiloxane composition, borosiloxane adhesive, coated and laminated substrates | DOW CORNING CORPORATION (US) | 2013-05-28 | — | — | US | disclosed |
| US-20110021736-A1 | Polyborosiloxane and Method of Preparing Same | DOW CORNING CORPORATION | 2011-01-27 | — | — | US | disclosed |
| US-20100316876-A1 | Borosiloxane Composition, Borosiloxane Adhesive, Coated and Laminated Substrates | DOW CORNING CORPORATION | 2010-12-16 | — | — | US | disclosed |
| EP-2254933-A1 | POLYBOROSILOXANE AND METHOD OF PREPARING SAME | Dow Corning Corporation (US) | 2010-12-01 | — | — | EP | disclosed |
| EP-2254934-A1 | BOROSILOXANE COMPOSITION, BOROSILOXANE ADHESIVE, COATED AND LAMINATED SUBSTRATES | Dow Corning Corporation (US) | 2010-12-01 | — | — | EP | disclosed |
| WO-2009111193-A1 | BOROSILOXANE COMPOSITION, BOROSILOXANE ADHESIVE, COATED AND LAMINATED SUBSTRATES | DOW CORNING CORPORATION (US) | 2009-09-11 | — | — | WO | disclosed |
| WO-2009111191-A1 | POLYBOROSILOXANE AND METHOD OF PREPARING SAME | DOW CORNING CORPORATION (US) | 2009-09-11 | — | — | WO | disclosed |