Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | IDO1 | P14902 | 1/20 | 0.48 |
| ▸ | AGXT | P21549 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL723193 | 0.79 | TSHR (0.57) | TSHRIDO1AGXTALDH1A1L3MBTL1 | |
| SCHEMBL1162782 | 0.76 | TSHR (0.48) | TSHRIDO1AGXTALDH1A1L3MBTL1 | |
| SCHEMBL7712856 | 0.76 | TSHR (0.48) | TSHRIDO1AGXTALDH1A1L3MBTL1 | |
| SCHEMBL30186261 | 0.75 | TSHR (0.52) | TSHRIDO1AGXTALDH1A1L3MBTL1 | |
| SCHEMBL1690445 | 0.75 | TSHR (0.52) | TSHRIDO1AGXTALDH1A1L3MBTL1 | |
| SCHEMBL6132100 | 0.71 | IDO1 (0.56) | TSHRIDO1AGXTALDH1A1L3MBTL1 | |
| SCHEMBL29866628 | 0.71 | TSHR (0.48) | TSHRIDO1AGXTALDH1A1L3MBTL1 | |
| SCHEMBL462297 | 0.70 | — | — | |
| SCHEMBL50083 | 0.70 | — | — | |
| SCHEMBL794 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8450442-B2 | Borosiloxane composition, borosiloxane adhesive, coated and laminated substrates | DOW CORNING CORPORATION (US) | 2013-05-28 | — | — | US | disclosed |
| US-20110021736-A1 | Polyborosiloxane and Method of Preparing Same | DOW CORNING CORPORATION | 2011-01-27 | — | — | US | disclosed |
| US-20100316876-A1 | Borosiloxane Composition, Borosiloxane Adhesive, Coated and Laminated Substrates | DOW CORNING CORPORATION | 2010-12-16 | — | — | US | disclosed |
| EP-2254933-A1 | POLYBOROSILOXANE AND METHOD OF PREPARING SAME | Dow Corning Corporation (US) | 2010-12-01 | — | — | EP | disclosed |
| EP-2254934-A1 | BOROSILOXANE COMPOSITION, BOROSILOXANE ADHESIVE, COATED AND LAMINATED SUBSTRATES | Dow Corning Corporation (US) | 2010-12-01 | — | — | EP | disclosed |
| WO-2009111193-A1 | BOROSILOXANE COMPOSITION, BOROSILOXANE ADHESIVE, COATED AND LAMINATED SUBSTRATES | DOW CORNING CORPORATION (US) | 2009-09-11 | — | — | WO | disclosed |
| WO-2009111191-A1 | POLYBOROSILOXANE AND METHOD OF PREPARING SAME | DOW CORNING CORPORATION (US) | 2009-09-11 | — | — | WO | disclosed |