Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 11/20 | 0.74 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | CA12 | O43570 | 1/20 | 0.53 |
| ▸ | BRD4 | O60885 | 1/20 | 0.53 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | MB | P02144 | 1/20 | 0.53 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.53 |
| ▸ | CA3 | P07451 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | RARG | P13631 | 1/20 | 0.53 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.53 |
| ▸ | CA4 | P22748 | 1/20 | 0.53 |
| ▸ | CA7 | P43166 | 1/20 | 0.53 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8810371 | 1.00 | DHODH (0.74) | DHODHMEN1KMT2AALDH1A1CYP3A4 | |
| SCHEMBL13531076 | 0.88 | DHODH (0.72) | DHODHMEN1KMT2AALDH1A1CYP3A4 | |
| SCHEMBL12202668 | 0.88 | DHODH (0.72) | DHODHMEN1KMT2AALDH1A1CYP3A4 | |
| SCHEMBL3250475 | 0.88 | DHODH (0.82) | DHODHMEN1KMT2AALDH1A1CYP3A4 | |
| SCHEMBL3250476 | 0.88 | DHODH (0.82) | DHODHMEN1KMT2AALDH1A1CYP3A4 | |
| SCHEMBL5914902 | 0.88 | DHODH (0.82) | DHODHMEN1KMT2AALDH1A1CYP3A4 | |
| SCHEMBL5914890 | 0.87 | DHODH (0.70) | DHODHMEN1KMT2AALDH1A1CYP3A4 | |
| SCHEMBL5914911 | 0.87 | DHODH (0.71) | DHODHMEN1KMT2AALDH1A1CYP3A4 | |
| SCHEMBL5914889 | 0.87 | DHODH (0.70) | DHODHMEN1KMT2AALDH1A1CYP3A4 | |
| SCHEMBL5914891 | 0.87 | DHODH (0.70) | DHODHMEN1KMT2AALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5532259-A | ANTITUMOR | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-07-02 | — | — | US | disclosed |
| US-5494911-A | TREATING LEUKEMIA, SARCOMA, CARCINOMA, LYMPHOMA, SKIN CANCER | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-02-27 | — | — | US | disclosed |