SCHEMBL9079869

SCHEMBL9079869

C[C@](N)(Cc1ccc(OCc2ccccc2)cc1)C(=O)O

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BLM P54132 1/20 0.62
PPARG P37231 4/20 0.57
MAOB P27338 3/20 0.55
PARP10 Q53GL7 1/20 0.55
L3MBTL1 Q9Y468 2/20 0.54
GAA P10253 1/20 0.54
MAPT P10636 1/20 0.54
MAOA P21397 1/20 0.54
RAB9A P51151 1/20 0.54
SMN1; SMN2 Q16637 1/20 0.54
NR4A1 P22736 1/20 0.54
NR4A2 P43354 1/20 0.54
NR4A3 Q92570 1/20 0.54
FFAR1 O14842 1/20 0.54
FFAR4 Q5NUL3 1/20 0.54
ALOX5 P09917 2/20 0.54
PPARA Q07869 2/20 0.53
PPARD Q03181 1/20 0.53
PTGS1 P23219 2/20 0.52
PTGS2 P35354 2/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30787972 1.00 BLM (0.62) BLMPPARGMAOBPARP10L3MBTL1
SCHEMBL9001028 1.00 BLM (0.62) BLMPPARGMAOBPARP10L3MBTL1
Bromide SCHEMBL7338094 0.99 BLM (0.60) BLMPPARGMAOBPARP10L3MBTL1
SCHEMBL27309675 0.90 PARP10 (0.57) PPARGMAOBPARP10L3MBTL1GAA
Hydrochloric Acid SCHEMBL27353104 0.89 PARP10 (0.56) PPARGMAOBPARP10L3MBTL1GAA
SCHEMBL7339430 0.86 MAOB (0.50) PPARGMAOBPARP10L3MBTL1GAA
SCHEMBL27311683 0.85 PPARG (0.53) BLMPPARGMAOBPARP10L3MBTL1
SCHEMBL7099922 0.85 PPARG (0.59) PPARGMAOBPARP10L3MBTL1GAA
SCHEMBL5326113 0.85 PPARG (0.59) PPARGMAOBPARP10L3MBTL1GAA
SCHEMBL27310687 0.84 NPC1 (0.51) PPARGMAOBPARP10MAPTRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024011333-A1 METHOD OF TREATING SKELETAL MUSCLE STEM CELL PATHOLOGIC DYSFUNCTION SOCPRA SCIENCES SANTÉ ET HUMAINES S.E.C. (CA) 2024-01-18 WO disclosed
EP-0725790-A1 SUBSTITUTED TETRA- AND PENTAPEPTIDE INHIBITORS OF PROTEIN:FARNESYL TRANSFERASE PARKE DAVIS & COMPANY (US) 1996-08-14 EP disclosed
WO-1995011917-A1 SUBSTITUTED TETRA- AND PENTAPEPTIDE INHIBITORS OF PROTEIN:FARNESYL TRANSFERASE PARKE, DAVIS & COMPANY (US) 1995-05-04 WO disclosed