SCHEMBL907997

SCHEMBL907997

C=C(C)C(=O)OC[C@@H](OC(=O)C(=C)C)[C@@H](O)[C@H](O)[C@@H](O)C=O

nearest known ligand 0.46

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.46
THRB P10828 1/20 0.33
ALDH1A1 P00352 1/20 0.32
TDP1 Q9NUW8 1/20 0.30
CYP2D6 P10635 1/20 0.30
CYP2C19 P33261 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8514077 1.00 TSHR (0.46) TSHRTHRBALDH1A1TDP1CYP2D6
SCHEMBL2491803 1.00 TSHR (0.46) TSHRTHRBALDH1A1TDP1CYP2D6
SCHEMBL2491059 0.88 TSHR (0.44) TSHRTHRBALDH1A1TDP1
SCHEMBL2489332 0.88 TSHR (0.44) TSHRTHRBALDH1A1TDP1
SCHEMBL2489438 0.88 TSHR (0.44) TSHRTHRBALDH1A1TDP1
SCHEMBL2491454 0.84 TSHR (0.45) TSHRTHRBALDH1A1TDP1
SCHEMBL2492155 0.84 TSHR (0.45) TSHRTHRBALDH1A1TDP1
SCHEMBL8512416 0.84 TSHR (0.45) TSHRTHRBALDH1A1TDP1
SCHEMBL4277422 0.83 TSHR (0.50) TSHRTHRBALDH1A1
SCHEMBL4274441 0.83 TSHR (0.50) TSHRTHRBALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 147 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114533939-A Preparation method of monodisperse sodium polyacrylate embolism microsphere 苏州森康微球医疗科技有限公司 2022-05-27 CN claimed
CN-114470308-A Preparation process of macroporous sodium polyacrylate embolism microsphere 苏州森康微球医疗科技有限公司 2022-05-13 CN claimed
US-8294975-B2 Automotive rearview mirror assembly DONNELLY CORPORATION (US) 2012-10-23 US claimed
US-20100110523-A1 AUTOMOTIVE REARVIEW MIRROR ASSEMBLY DONNELLY CORPORATION (US) 2010-05-06 US claimed
US-7202987-B2 Electrochromic polymeric solid films, manufacturing electrochromic devices using such solid films, and processes for making such solid films and devices DONNELLY CORPORATION (US) 2007-04-10 US claimed
US-6954300-B2 Electrochromic polymeric solid films, manufacturing electrochromic devices using such sold films, and processes for making such solid films and devices DONNELLY CORPORATION (US) 2005-10-11 US claimed
US-20050079326-A1 Electrochromic polymeric solid films, manufacturing electrochromic devices using such solid films, and processes for making such solid films and devices DONNELLY CORPORATION (US) 2005-04-14 US claimed
US-6154306-A Electrochromic polymeric solid films, manufacturing electrochromic devices using such solid films, and processes for making such solid films and devices DONNELLY CORPORATION (US) 2000-11-28 US claimed
EP-0612826-B1 Electrochromic polymeric solid films, manufacturing electrochromic devices using such solid films, and processing for making such solid films and devices DONNELLY CORP (US) 2000-10-04 EP claimed
EP-1004649-A2 Electrochromic polymeric solid films, manufacturing electrochromic devices using such solid films, and processes for making such solid films and devices DONNELLY CORPORATION (US) 2000-05-31 EP claimed
US-6002511-A Electrochromic polymeric solid films, manufacturing electrochromic devices using such solid films, and processes for making such solid films and devices DONNELLY CORPORATION (US) 1999-12-14 US claimed
EP-0425436-B1 Reactive silicone and/or fluorine containing hydrophilic prepolymers and polymers thereof CIBA GEIGY AG (CH) 1996-12-27 EP claimed
EP-0612826-A1 Electrochromic polymeric solid films, manufacturing electrochromic devices using such solid films, and processing for making such solid films and devices DONNELLY CORPORATION (US) 1994-08-31 EP claimed
US-5079319-A Contact Lenses CIBA-GEIGY CORPORATION (US) 1992-01-07 US claimed
EP-0425436-A2 Reactive silicone and/or fluorine containing hydrophilic prepolymers and polymers thereof CIBA-GEIGY AG (CH) 1991-05-02 EP claimed
US-4082894-A COATING WITH PRIMER POLYMER, DRYING, CURING MELAMINE-TYPE RESIN COATING NIPPON SHEET GLASS CO., LTD. (JA) 1978-04-04 US claimed
CN-112704774-B Hemoperfusion apparatus filled with immobilized L-asparaginase and preparation method and application thereof 苏州森康微球医疗科技有限公司 2023-01-10 CN disclosed
CN-114533939-A Preparation method of monodisperse sodium polyacrylate embolism microsphere 苏州森康微球医疗科技有限公司 2022-05-27 CN disclosed
US-3935368-A Vinyl chloride flooring material coated with a hydrophilic acrylic polymer NATIONAL PATENT DEVELOPMENT CORPORATION (US) 1976-01-27 US disclosed
US-3935342-A POLYMERIZATION WITH AN UNSATURATED SILYL MONOMER MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) 1976-01-27 US disclosed