Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | STAT3 | P40763 | 4/20 | 0.54 |
| ▸ | LPAR1 | Q92633 | 9/20 | 0.48 |
| ▸ | LPAR5 | Q9H1C0 | 9/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9080511 | 1.00 | TSHR (0.59) | TSHRTDP1STAT3LPAR1LPAR5 | |
| SCHEMBL9081827 | 0.96 | TSHR (0.60) | TSHRTDP1STAT3LPAR1LPAR5 | |
| SCHEMBL9080531 | 0.94 | TSHR (0.55) | TSHRTDP1STAT3LPAR1LPAR5 | |
| SCHEMBL9081721 | 0.94 | TSHR (0.55) | TSHRTDP1STAT3LPAR1LPAR5 | |
| SCHEMBL9080371 | 0.94 | TSHR (0.55) | TSHRTDP1STAT3LPAR1LPAR5 | |
| SCHEMBL9081215 | 0.94 | TSHR (0.55) | TSHRTDP1STAT3LPAR1LPAR5 | |
| SCHEMBL9081031 | 0.92 | TSHR (0.53) | TSHRTDP1STAT3LPAR1LPAR5 | |
| SCHEMBL9080843 | 0.88 | TSHR (0.53) | TSHRTDP1STAT3LPAR1LPAR5 | |
| SCHEMBL9080541 | 0.88 | TSHR (0.53) | TSHRTDP1STAT3LPAR1LPAR5 | |
| SCHEMBL9080924 | 0.86 | TSHR (0.67) | TSHRTDP1LPAR1LPAR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996034851-A1 | BENZENE, PYRIDINE, NAPHTALENE OR BENZOPHENONE DERIVATIVES AS INHIBITORS OF SQUALENE SYNTHETASE AND PROTEIN FARNESYLTRANSFERASE | ABBOTT LABORATORIES (US) | 1996-11-07 | — | — | WO | disclosed |