Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 14/20 | 0.58 |
| ▸ | LPAR5 | Q9H1C0 | 13/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | STAT3 | P40763 | 2/20 | 0.53 |
| ▸ | PTGES | O14684 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9080525 | 0.93 | LPAR1 (0.58) | LPAR1LPAR5POLBPTGES | |
| SCHEMBL9081181 | 0.91 | POLB (0.56) | LPAR1LPAR5POLBSTAT3PTGES | |
| SCHEMBL9081195 | 0.91 | LPAR1 (0.57) | LPAR1LPAR5STAT3PTGESTSHR | |
| SCHEMBL9081830 | 0.91 | LPAR1 (0.57) | LPAR1LPAR5STAT3PTGESTSHR | |
| SCHEMBL9081224 | 0.90 | POLB (0.55) | LPAR1LPAR5POLBSTAT3PTGES | |
| SCHEMBL9080814 | 0.88 | POLB (0.51) | LPAR1LPAR5POLBSTAT3PTGES | |
| SCHEMBL9079915 | 0.87 | LPAR1 (0.58) | LPAR1LPAR5 | |
| SCHEMBL9081236 | 0.87 | LPAR1 (0.53) | LPAR1LPAR5STAT3 | |
| SCHEMBL9081215 | 0.87 | TSHR (0.55) | LPAR1LPAR5STAT3TSHR | |
| SCHEMBL9080371 | 0.87 | TSHR (0.55) | LPAR1LPAR5STAT3TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996034851-A1 | BENZENE, PYRIDINE, NAPHTALENE OR BENZOPHENONE DERIVATIVES AS INHIBITORS OF SQUALENE SYNTHETASE AND PROTEIN FARNESYLTRANSFERASE | ABBOTT LABORATORIES (US) | 1996-11-07 | — | — | WO | claimed |
| WO-1996034851-A1 | BENZENE, PYRIDINE, NAPHTALENE OR BENZOPHENONE DERIVATIVES AS INHIBITORS OF SQUALENE SYNTHETASE AND PROTEIN FARNESYLTRANSFERASE | ABBOTT LABORATORIES (US) | 1996-11-07 | — | — | WO | disclosed |