Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.53 |
| ▸ | HTR2B | P41595 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.53 |
| ▸ | RECQL | P46063 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | HTR2C | P28335 | 4/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | PTGER3 | P43115 | 6/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9081223 | 0.90 | HTR2B (0.58) | CYP1A2HTR2BMEN1TP53CYP3A4 | |
| SCHEMBL9082800 | 0.89 | HTR2B (0.52) | CYP1A2HTR2BMEN1TP53CYP3A4 | |
| SCHEMBL9082259 | 0.89 | MAPT (0.52) | CYP1A2HTR2BMEN1TP53CYP3A4 | |
| SCHEMBL9080741 | 0.89 | MEN1 (0.55) | CYP1A2HTR2BMEN1TP53CYP3A4 | |
| SCHEMBL9081740 | 0.88 | HTR2B (0.54) | CYP1A2HTR2BMEN1TP53CYP3A4 | |
| SCHEMBL9082827 | 0.88 | MEN1 (0.54) | CYP1A2HTR2BMEN1TP53CYP3A4 | |
| SCHEMBL9081809 | 0.87 | KDM4E (0.50) | CYP1A2HTR2BMEN1TP53CYP3A4 | |
| SCHEMBL9080815 | 0.85 | HTR2B (0.55) | CYP1A2HTR2BMEN1TP53CYP3A4 | |
| SCHEMBL9081805 | 0.83 | HTR2B (0.50) | CYP1A2HTR2BMEN1TP53CYP3A4 | |
| SCHEMBL9081780 | 0.83 | HTR2B (0.58) | CYP1A2HTR2BMEN1TP53CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996039382-A1 | UREA DERIVATIVES AS 5-HT ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-12-12 | — | — | WO | disclosed |