Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | HRH1 | P35367 | 1/20 | 0.52 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | LIN28A | Q9H9Z2 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL229256 | 0.84 | KDM4E (0.58) | KDM4ETDP1TSHRNPSR1POLB | |
| SCHEMBL31059180 | 0.84 | KDM4E (0.68) | KDM4ETDP1TSHRNPSR1POLB | |
| SCHEMBL12819456 | 0.84 | KDM4E (0.68) | KDM4ETDP1TSHRNPSR1POLB | |
| SCHEMBL31059181 | 0.84 | KDM4E (0.68) | KDM4ETDP1TSHRNPSR1POLB | |
| SCHEMBL30086100 | 0.84 | KDM4E (0.58) | KDM4ETDP1TSHRNPSR1POLB | |
| Hydrochloric Acid SCHEMBL29367467 | 0.82 | KDM4E (0.57) | KDM4ETDP1TSHRNPSR1POLB | |
| SCHEMBL14048279 | 0.81 | KDM4E (0.55) | KDM4ETDP1TSHRNPSR1POLB | |
| SCHEMBL6785130 | 0.80 | KDM4E (0.59) | KDM4ETDP1TSHRNPSR1POLB | |
| SCHEMBL14191759 | 0.80 | KDM4E (0.51) | KDM4ETDP1TSHRNPSR1POLB | |
| SCHEMBL3459116 | 0.80 | TDP1 (0.59) | KDM4ETDP1TSHRNPSR1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996034866-A1 | IMIDAZO 1,2-A PYRIDINE AND IMIDAZO 1,2-A PYRIDEZINE DERIVATIVES AND THEIR USE AS BONE RESORPTION INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-11-07 | — | — | WO | disclosed |