Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR4 | O00206 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | F7 | P08709 | 2/20 | 0.46 |
| ▸ | F3 | P13726 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.46 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.46 |
| ▸ | OXER1 | Q8TDS5 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10385049 | 1.00 | TLR4 (0.52) | TLR4ALDH1A1CYP3A4ALOX15HSD17B10 | |
| SCHEMBL2196896 | 0.93 | TLR4 (0.59) | TLR4CETP | |
| SCHEMBL2196886 | 0.93 | TLR4 (0.59) | TLR4CETP | |
| SCHEMBL5436079 | 0.93 | TLR4 (0.59) | TLR4CETP | |
| SCHEMBL1758430 | 0.93 | TLR4 (0.59) | TLR4CETP | |
| SCHEMBL2196892 | 0.93 | TLR4 (0.59) | TLR4CETP | |
| SCHEMBL2201431 | 0.93 | TLR4 (0.59) | TLR4CETP | |
| SCHEMBL9347370 | 0.93 | TLR4 (0.51) | TLR4ALDH1A1CYP3A4ALOX15HSD17B10 | |
| SCHEMBL4193269 | 0.90 | TLR4 (0.49) | TLR4ALDH1A1CYP3A4ALOX15HSD17B10 | |
| SCHEMBL4193271 | 0.90 | TLR4 (0.49) | TLR4ALDH1A1CYP3A4ALOX15HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0719318-A1 | A METHOD FOR REMOVING SILICONE FLUIDS | NOVO NORDISK A/S (DK) | 1996-07-03 | — | — | EP | disclosed |
| WO-1995007967-A1 | A METHOD FOR REMOVING SILICONE FLUIDS | NOVO NORDISK A/S (DK) | 1995-03-23 | — | — | WO | disclosed |