Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.63 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.63 |
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | THPO | P40225 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | APEX1 | P27695 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9083164 | 1.00 | CYP3A4 (0.63) | CYP3A4SLC7A5HRH4HRH3ALDH1A1 | |
| SCHEMBL1537285 | 0.94 | CYP3A4 (0.71) | CYP3A4SLC7A5HRH4HRH3ALDH1A1 | |
| SCHEMBL163444 | 0.94 | CYP3A4 (0.71) | CYP3A4SLC7A5HRH4HRH3ALDH1A1 | |
| Hydrochloric Acid SCHEMBL28331180 | 0.92 | CYP3A4 (0.69) | CYP3A4SLC7A5HRH4HRH3ALDH1A1 | |
| SCHEMBL8373019 | 0.89 | CYP3A4 (0.60) | CYP3A4SLC7A5HRH4HRH3ALDH1A1 | |
| SCHEMBL15911724 | 0.88 | CYP3A4 (0.63) | CYP3A4SLC7A5HRH4HRH3ALDH1A1 | |
| SCHEMBL28328192 | 0.88 | CYP3A4 (0.67) | CYP3A4SLC7A5HRH4HRH3ALDH1A1 | |
| SCHEMBL6426905 | 0.87 | CYP3A4 (0.58) | CYP3A4SLC7A5HRH4HRH3ALDH1A1 | |
| SCHEMBL5652907 | 0.87 | CYP3A4 (0.58) | CYP3A4SLC7A5HRH4HRH3ALDH1A1 | |
| SCHEMBL17223938 | 0.87 | CYP3A4 (0.52) | CYP3A4SLC7A5HRH4HRH3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3714902-B1 | STABILIZATION OF PHARMACEUTICAL COMPOSITIONS COMPRISING POLYSORBATE | LEK PHARMACEUTICALS (SI) | 2024-08-28 | — | — | EP | claimed |
| US-20230137216-A1 | Stabilization of Pharmaceutical Compositions Comprising Polysorbate | LEK PHARMACEUTICALS D.D. (SI) | 2023-05-04 | — | — | US | claimed |
| WO-2021180981-A1 | STABILIZATION OF PHARMACEUTICAL COMPOSITIONS COMPRISING POLYSORBATE | LEK PHARMACEUTICALS D.D. (SI) | 2021-09-16 | — | — | WO | claimed |
| EP-3714902-A1 | STABILIZATION OF PHARMACEUTICAL COMPOSITIONS COMPRISING POLYSORBATE | LEK Pharmaceuticals d.d. (SI) | 2020-09-30 | — | — | EP | claimed |
| EP-4683615-A1 | FORMULATIONS COMPRISING POLYSORBATE | Boehringer Ingelheim International GmbH (DE) | 2026-01-28 | — | — | EP | disclosed |
| WO-2024194421-A1 | FORMULATIONS COMPRISING POLYSORBATE | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2024-09-26 | — | — | WO | disclosed |
| EP-3714902-B1 | STABILIZATION OF PHARMACEUTICAL COMPOSITIONS COMPRISING POLYSORBATE | LEK PHARMACEUTICALS (SI) | 2024-08-28 | — | — | EP | disclosed |
| US-20230137216-A1 | Stabilization of Pharmaceutical Compositions Comprising Polysorbate | LEK PHARMACEUTICALS D.D. (SI) | 2023-05-04 | — | — | US | disclosed |
| WO-2021180981-A1 | STABILIZATION OF PHARMACEUTICAL COMPOSITIONS COMPRISING POLYSORBATE | LEK PHARMACEUTICALS D.D. (SI) | 2021-09-16 | — | — | WO | disclosed |
| EP-3714902-A1 | STABILIZATION OF PHARMACEUTICAL COMPOSITIONS COMPRISING POLYSORBATE | LEK Pharmaceuticals d.d. (SI) | 2020-09-30 | — | — | EP | disclosed |
| US-5496955-A | RESOLUTION OF ISOMERS BY REACTION WITH ALDEHYDE IN ACETIC ACID AND TARTARIC ACID | BROMINE COMPOUNDS LIMITED (IL) | 1996-03-05 | — | — | US | disclosed |
| EP-0465974-A1 | Preparation of D-histidine and derivatives thereof from L-histidine | Bromine Compounds Ltd. (IL) | 1992-01-15 | — | — | EP | disclosed |