Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 19/20 | 0.56 |
| ▸ | LPAR5 | Q9H1C0 | 16/20 | 0.56 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9081632 | 0.95 | LPAR1 (0.53) | LPAR1LPAR5LPAR3 | |
| SCHEMBL9081773 | 0.92 | LPAR1 (0.53) | LPAR1LPAR5LPAR3 | |
| SCHEMBL9080294 | 0.90 | LPAR1 (0.52) | LPAR1LPAR5LPAR3 | |
| SCHEMBL9081031 | 0.90 | TSHR (0.53) | LPAR1LPAR5 | |
| SCHEMBL9080371 | 0.89 | TSHR (0.55) | LPAR1LPAR5 | |
| SCHEMBL9080531 | 0.89 | TSHR (0.55) | LPAR1LPAR5 | |
| SCHEMBL9081721 | 0.89 | TSHR (0.55) | LPAR1LPAR5 | |
| SCHEMBL9081215 | 0.89 | TSHR (0.55) | LPAR1LPAR5 | |
| SCHEMBL9081637 | 0.87 | LPAR1 (0.54) | LPAR1LPAR5 | |
| SCHEMBL9081403 | 0.86 | MEN1 (0.62) | LPAR1LPAR5LPAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996034851-A1 | BENZENE, PYRIDINE, NAPHTALENE OR BENZOPHENONE DERIVATIVES AS INHIBITORS OF SQUALENE SYNTHETASE AND PROTEIN FARNESYLTRANSFERASE | ABBOTT LABORATORIES (US) | 1996-11-07 | — | — | WO | disclosed |