Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL446501 | 0.82 | MAPT (0.64) | MAPTALDH1A1MEN1KMT2ACYP3A4 | |
| SCHEMBL21480659 | 0.82 | MAPT (0.64) | MAPTALDH1A1MEN1KMT2ACYP3A4 | |
| SCHEMBL6983298 | 0.81 | MAPT (0.68) | MAPTALDH1A1MEN1KMT2ACYP3A4 | |
| SCHEMBL4221 | 0.81 | — | — | |
| SCHEMBL8891623 | 0.81 | MAPT (0.60) | MAPTALDH1A1MEN1KMT2ACYP3A4 | |
| SCHEMBL237380 | 0.81 | MAPT (0.60) | MAPTALDH1A1MEN1KMT2ACYP3A4 | |
| SCHEMBL2375356 | 0.81 | MAPT (0.60) | MAPTALDH1A1MEN1KMT2ACYP3A4 | |
| SCHEMBL13116800 | 0.81 | MAPT (0.62) | MAPTALDH1A1MEN1KMT2ACYP3A4 | |
| SCHEMBL6990807 | 0.81 | MAPT (0.62) | MAPTALDH1A1MEN1KMT2ACYP3A4 | |
| Hydrochloric Acid SCHEMBL9704969 | 0.81 | MAPT (0.62) | MAPTALDH1A1MEN1KMT2ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106278999-B | S1P regulator | 比奥根MA公司 | 2019-10-25 | — | — | CN | disclosed |
| CN-106278999-A | S1p regulator | 比奥根MA公司 | 2017-01-04 | — | — | CN | disclosed |
| WO-1996034866-A1 | IMIDAZO 1,2-A PYRIDINE AND IMIDAZO 1,2-A PYRIDEZINE DERIVATIVES AND THEIR USE AS BONE RESORPTION INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-11-07 | — | — | WO | disclosed |