Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.58 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.58 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.58 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.55 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.55 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.55 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.55 |
| ▸ | GSK3B | P49841 | 6/20 | 0.48 |
| ▸ | TOP2A | P11388 | 2/20 | 0.46 |
| ▸ | TOP2B | Q02880 | 2/20 | 0.46 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.44 |
| ▸ | MATK | P42679 | 1/20 | 0.44 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8852523 | 0.99 | POLB (0.58) | POLBALDH1A1OPRM1CHRM2CHRM1 | |
| SCHEMBL10509371 | 0.89 | MEN1 (0.70) | POLBALDH1A1OPRM1CHRM2CHRM1 | |
| SCHEMBL8922019 | 0.87 | POLB (0.72) | POLBALDH1A1OPRM1CHRM2CHRM1 | |
| SCHEMBL8110587 | 0.87 | POLB (0.61) | POLBALDH1A1OPRM1CHRM2CHRM1 | |
| SCHEMBL8116699 | 0.86 | POLB (0.58) | POLBALDH1A1OPRM1CHRM2CHRM1 | |
| SCHEMBL9231288 | 0.86 | POLB (0.47) | POLBALDH1A1OPRM1CHRM2CHRM1 | |
| SCHEMBL9088303 | 0.85 | POLB (0.59) | POLBALDH1A1OPRM1CHRM2CHRM1 | |
| Hydrochloric Acid SCHEMBL9368352 | 0.85 | POLB (0.69) | POLBALDH1A1OPRM1CHRM2CHRM1 | |
| SCHEMBL8888963 | 0.85 | POLB (0.58) | POLBALDH1A1OPRM1CHRM2CHRM1 | |
| SCHEMBL8888976 | 0.85 | POLB (0.58) | POLBALDH1A1OPRM1CHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5578604-A | BACTERICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1996-11-26 | — | — | US | claimed |
| EP-0671391-A1 | 5-Vinyl- and 5-ethinyl-quinolinone- and -naphthyridone-carboxylic acids | BAYER AG (DE) | 1995-09-13 | — | — | EP | claimed |
| EP-0671391-A1 | 5-Vinyl- and 5-ethinyl-quinolinone- and -naphthyridone-carboxylic acids | BAYER AG (DE) | 1995-09-13 | — | — | EP | disclosed |