SCHEMBL9083271

SCHEMBL9083271

CCCC1C(=O)N(COC(=O)c2c(Cl)cccc2Cl)S(=O)(=O)N1CC

nearest known ligand 0.80

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ELANE P08246 20/20 0.80

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7423404 0.89 ELANE (1.00) ELANE
SCHEMBL7426990 0.77 ELANE (0.78) ELANE
SCHEMBL7478668 0.77 ELANE (0.65) ELANE
SCHEMBL7594146 0.75 ELANE (0.75) ELANE
SCHEMBL9083677 0.73 ELANE (0.69) ELANE
SCHEMBL9083706 0.70 ELANE (0.56) ELANE
SCHEMBL9083100 0.70 ELANE (0.58) ELANE
SCHEMBL9083819 0.69 ELANE (0.54) ELANE
SCHEMBL8493097 0.65 CA12 (0.66) ELANE
SCHEMBL8866035 0.65 ELANE (0.88) ELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5556909-A PROTEOLYTIC ENZYME INHIBITOR, TREATMENT OF DEGENERATIVE DISEASES, SUCH AS EMPHYSEMA, RHEUMATOID ARTHRITIS AND PANCREATITIS SANOFI WINTHROP INC. (US) 1996-09-17 US disclosed