SCHEMBL9083752

SCHEMBL9083752

COc1c(I)cc(C(C)C)c(C=C[C@H]2C[C@H](O)CC(=O)O2)c1-c1ccc(F)cc1

nearest known ligand 0.60

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
HMGCR P04035 10/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9083743 1.00 HMGCR (0.60) HMGCR
SCHEMBL9083747 1.00 HMGCR (0.60) HMGCR
SCHEMBL9083735 1.00 HMGCR (0.60) HMGCR
SCHEMBL9083778 0.92 HMGCR (0.61) HMGCR
SCHEMBL9083786 0.92 HMGCR (0.61) HMGCR
SCHEMBL9410860 0.92 HMGCR (0.61) HMGCR
SCHEMBL9410861 0.92 HMGCR (0.61) HMGCR
SCHEMBL9086136 0.91 HMGCR (0.60) HMGCR
SCHEMBL9410854 0.91 HMGCR (0.60) HMGCR
SCHEMBL9086116 0.91 HMGCR (0.60) HMGCR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5523460-A ANTICHOLESTEROL AGENTS FUJIREBIO INC. (JP) 1996-06-04 US disclosed