Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 2/20 | 0.85 |
| ▸ | TRPV1 | Q8NER1 | 11/20 | 0.69 |
| ▸ | CA1 | P00915 | 5/20 | 0.69 |
| ▸ | CA2 | P00918 | 5/20 | 0.69 |
| ▸ | CA7 | P43166 | 5/20 | 0.69 |
| ▸ | CA9 | Q16790 | 5/20 | 0.69 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.65 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.62 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.61 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.61 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9084605 | 0.93 | KDR (0.72) | KDRTRPV1CA1CA2CA7 | |
| SCHEMBL118026 | 0.92 | KDR (1.00) | KDRTRPV1CA1CA2CA7 | |
| SCHEMBL29364392 | 0.92 | KDR (1.00) | KDRTRPV1CA1CA2CA7 | |
| SCHEMBL21751016 | 0.90 | KDR (0.78) | KDRTRPV1CA1CA2CA7 | |
| SCHEMBL281864 | 0.88 | KDR (0.85) | KDRTRPV1CA1CA2CA7 | |
| SCHEMBL4548158 | 0.88 | KDR (0.90) | KDRTRPV1CA1CA2CA7 | |
| SCHEMBL10220062 | 0.86 | KDR (0.88) | KDRTRPV1CA1CA2CA7 | |
| Cloflucarban SCHEMBL119821 | 0.86 | KDR (0.88) | KDRTRPV1CA1CA2CA7 | |
| Cloflucarban SCHEMBL27537485 | 0.86 | KDR (0.88) | KDRTRPV1CA1CA2CA7 | |
| SCHEMBL19677976 | 0.86 | KDR (0.88) | KDRTRPV1CA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5541224-A | ANIMAL FEEDS | ELI LILLY AND COMPANY (US) | 1996-07-30 | — | — | US | disclosed |