Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9089557 | 0.87 | KDM4E (0.42) | KDM4EHTTLMNAMAPTATM | |
| SCHEMBL9085324 | 0.87 | KDM4E (0.42) | KDM4EHTTLMNAMAPTATM | |
| SCHEMBL8624063 | 0.81 | KDM4E (0.38) | KDM4EHTTLMNAMAPTATM | |
| SCHEMBL9088638 | 0.81 | KDM4E (0.38) | KDM4EHTTLMNAMAPTATM | |
| SCHEMBL9090437 | 0.81 | KDM4E (0.38) | KDM4EHTTLMNAMAPTATM | |
| SCHEMBL9088605 | 0.79 | KDM4E (0.36) | KDM4EHTTLMNAMAPT | |
| SCHEMBL9088744 | 0.78 | HTT (0.43) | KDM4EHTTLMNAMAPTATM | |
| SCHEMBL8630585 | 0.76 | KDM4E (0.47) | KDM4EHTTLMNAMAPTATM | |
| SCHEMBL9089133 | 0.76 | MAPT (0.47) | KDM4EHTTLMNAMAPTALDH1A1 | |
| SCHEMBL8311060 | 0.71 | KDM4E (0.37) | KDM4EHTTLMNAMAPTATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5585491-A | Antibacterial agents | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1996-12-17 | — | — | US | disclosed |
| EP-0398967-A1 | ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY (US) | 1990-11-28 | — | — | EP | disclosed |
| US-4920120-A | 3-CARBOXY, 4-OXO, 6-FLUORO, 7-NITROGEN-CONTAINING RING 1,4-DIHYDRO-1,8-NAPHTHYRIDINES | WARNER-LAMBERT COMPANY (US) | 1990-04-24 | — | — | US | disclosed |
| EP-0326891-A2 | Antibacterial agents | WARNER-LAMBERT COMPANY (US) | 1989-08-09 | — | — | EP | disclosed |
| WO-1989006649-A2 | ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY (US) | 1989-07-27 | — | — | WO | disclosed |