Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERBB2 | P04626 | 20/20 | 1.00 |
| ▸ | FLT1 | P17948 | 18/20 | 1.00 |
| ▸ | EPHA2 | P29317 | 17/20 | 1.00 |
| ▸ | KDR | P35968 | 14/20 | 1.00 |
| ▸ | EPHB4 | P54760 | 11/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL908569 | 1.00 | ERBB2 (1.00) | ERBB2FLT1EPHA2KDREPHB4 | |
| SCHEMBL12898300 | 1.00 | ERBB2 (1.00) | ERBB2FLT1EPHA2KDREPHB4 | |
| SCHEMBL13589108 | 1.00 | ERBB2 (1.00) | ERBB2FLT1EPHA2KDREPHB4 | |
| SCHEMBL906990 | 0.94 | ERBB2 (1.00) | ERBB2FLT1EPHA2KDREPHB4 | |
| SCHEMBL906737 | 0.91 | FLT1 (1.00) | ERBB2FLT1EPHA2KDREPHB4 | |
| SCHEMBL13590226 | 0.91 | FLT1 (1.00) | ERBB2FLT1EPHA2KDREPHB4 | |
| SCHEMBL13589090 | 0.91 | FLT1 (1.00) | ERBB2FLT1EPHA2KDREPHB4 | |
| SCHEMBL906721 | 0.91 | FLT1 (1.00) | ERBB2FLT1EPHA2KDREPHB4 | |
| SCHEMBL13589102 | 0.91 | FLT1 (1.00) | ERBB2FLT1EPHA2KDREPHB4 | |
| Hydrochloric Acid SCHEMBL907860 | 0.90 | FLT1 (0.99) | ERBB2FLT1EPHA2KDREPHB4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2277867-A2 | Compounds, pharmaceutical compositions thereof and their use in treating cancer | Symphony Evolution, Inc. (US) | 2011-01-26 | — | — | EP | disclosed |