Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | PADI1 | Q9ULC6 | 1/20 | 0.37 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.37 |
| ▸ | CXCR4 | P61073 | 2/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.33 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.33 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | RAD52 | P43351 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11264176 | 0.98 | SMN1; SMN2 (0.46) | SMN1; SMN2PADI1PADI4CXCR4SLC6A2 | |
| SCHEMBL27972835 | 0.90 | SMN1; SMN2 (0.41) | SMN1; SMN2PADI1PADI4SLC6A2CHRM5 | |
| SCHEMBL8972570 | 0.83 | SMN1; SMN2 (0.44) | SMN1; SMN2PADI1PADI4CXCR4SLC6A2 | |
| SCHEMBL3964702 | 0.81 | PIK3CD (0.33) | MEN1KMT2A | |
| SCHEMBL28343762 | 0.78 | SMN1; SMN2 (0.49) | SMN1; SMN2PADI1PADI4CXCR4SLC6A2 | |
| SCHEMBL11268764 | 0.77 | SMN1; SMN2 (0.47) | SMN1; SMN2PADI1PADI4CXCR4SLC6A2 | |
| SCHEMBL31586817 | 0.77 | SMN1; SMN2 (0.41) | SMN1; SMN2PADI1PADI4CXCR4CHRM5 | |
| SCHEMBL24462563 | 0.77 | SMN1; SMN2 (0.47) | SMN1; SMN2PADI1PADI4SLC6A2CHRM5 | |
| SCHEMBL27841858 | 0.77 | MEN1 (0.44) | SMN1; SMN2POLBMEN1KMT2A | |
| SCHEMBL8558443 | 0.76 | SMN1; SMN2 (0.44) | SMN1; SMN2PADI1PADI4CXCR4SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5539105-A | HYDROLYSIS AND FORMYLATION OF TETRAZOCYCLIC COMPOUNDS FOR CHELATE AGENTS | DIBRA S.P.A. (IT) | 1996-07-23 | — | — | US | disclosed |
| US-5424423-A | Disubstituted 1,4,7,10-tetraazacyclododecanes | DIBRA S.P.A. (IT) | 1995-06-13 | — | — | US | disclosed |
| EP-0545983-B1 | INTERMEDIATES FOR CHELATING AGENTS WITH PREFIXED SYMMETRY AND PROCESS FOR THEIR PREPARATION | BRACCO SPA (IT) | 1994-10-26 | — | — | EP | disclosed |
| WO-1992004336-A1 | INTERMEDIATES FOR CHELATING AGENTS WITH PREFIXED SYMMETRY AND PROCESS FOR THEIR PREPARATION | BRACCO INDUSTRIA CHIMICA S.P.A. (IT) | 1992-03-19 | — | — | WO | disclosed |