SCHEMBL908784

SCHEMBL908784

Nc1ccc(F)nc1F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29351065 1.00
SCHEMBL16644635 0.78
SCHEMBL30614556 0.78
SCHEMBL31163590 0.74
SCHEMBL20595762 0.74
SCHEMBL2956858 0.74
SCHEMBL14689378 0.74
SCHEMBL3230633 0.74
SCHEMBL9982792 0.74
SCHEMBL2067821 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 101 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3599854-B1 PYRROLIDINONES AND A PROCESS TO PREPARE THEM FMC CORP (US) 2026-05-06 EP disclosed
US-20260022095-A1 COMPOUNDS USEFUL FOR THE PREPARATION OF VARIOUS AGROCHEMICALS AND MARKERS THEREOF ADAMA AGAN LTD. (IL) 2026-01-22 US disclosed
US-20250346609-A1 COT MODULATORS AND METHODS OF USE THEREOF GILEAD SCIENCES INC (US) 2025-11-13 US disclosed
EP-4613332-A2 COT MODULATORS AND METHODS OF USE THEREOF Gilead Sciences, Inc. (US) 2025-09-10 EP disclosed
US-20250197350-A1 COMPOUNDS USEFUL FOR THE PREPARATION OF VARIOUS AGROCHEMICALS AND MARKERS THEREOF ADAMA AGAN LTD. (IL) 2025-06-19 US disclosed
EP-3896064-B1 4,6-DIAMINO-QUINOLINE-3-CARBONITRILE DERIVATIVES AS CANCER OSAKA THYROID (COT) MODULATORS FOR TREATING CROHN'S DISEASE AND ULCERATIVE COLITIS GILEAD SCIENCES INC (US) 2025-05-21 EP disclosed
US-20250066297-A1 COMPOUNDS USEFUL FOR THE PREPARATION OF VARIOUS AGROCHEMICALS AND MARKERS THEREOF ADAMA AGAN LTD. (IL) 2025-02-27 US disclosed
EP-4508980-A2 COMPOUNDS USEFUL FOR THE PREPARATION OF VARIOUS AGROCHEMICALS AND MARKERS THEREOF Adama Agan Ltd. (IL) 2025-02-19 EP disclosed
EP-4483714-A2 COMPOUNDS USEFUL FOR THE PREPARATION OF VARIOUS AGROCHEMICALS AND MARKERS THEREOF Adama Agan Ltd. (IL) 2025-01-01 EP disclosed
US-20240254137-A1 COT MODULATORS AND METHODS OF USE THEREOF GILEAD SCIENCES, INC. 2024-08-01 US disclosed
EP-2300481-A2 NOVEL SUBSTITUTED AZABENZOXAZOLES Merck Sharp & Dohme Corp. (US) 2011-03-30 EP disclosed
US-20110065696-A1 IMIDAZOYL PYRIDINE COMPOUNDS AND SALTS THEREOF KIMURA TEIJI 2011-03-17 US disclosed
US-20110009619-A1 POLYCYCLIC COMPOUND EISAI R&D MANAGEMENT CO., LTD. (JP) 2011-01-13 US disclosed
CN-101815713-A Polycyclic compounds EISAI R&D MAN CO LTD 2010-08-25 CN disclosed
WO-2010051196-A1 NOVEL SUBSTITUTED AZABENZOXAZOLES MERCK SHARP & DOHME CORP. (US) 2010-05-06 WO disclosed
WO-2010051196-A1 NOVEL SUBSTITUTED AZABENZOXAZOLES MERCK SHARP & DOHME CORP. (US) 2010-05-06 WO disclosed
EP-2181992-A1 POLYCYCLIC COMPOUND Eisai R&D Management Co., Ltd. (JP) 2010-05-05 EP disclosed
WO-2009155017-A2 NOVEL SUBSTITUTED AZABENZOXAZOLES MERCK & CO., INC. (US) 2009-12-23 WO disclosed
WO-2009155017-A2 NOVEL SUBSTITUTED AZABENZOXAZOLES MERCK & CO., INC. (US) 2009-12-23 WO disclosed
US-20090062529-A1 MULTI-CYCLIC COMPOUNDS EISAI R&D MANAGEMENT CO., LTD., (JP) 2009-03-05 US disclosed