SCHEMBL9090652

SCHEMBL9090652

CCOC(=O)CNc1nc(Cl)nc(Cl)n1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.68
HTT P42858 1/20 0.68
MAPK1 P28482 1/20 0.67
KMT2A Q03164 3/20 0.52
MEN1 O00255 2/20 0.52
ALDH1A1 P00352 4/20 0.50
POLB P06746 2/20 0.50
LMNA P02545 1/20 0.46
CA12 O43570 2/20 0.44
CA1 P00915 2/20 0.44
CA2 P00918 2/20 0.44
CA9 Q16790 2/20 0.44
CA14 Q9ULX7 2/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
GAA P10253 3/20 0.42
MGAM O43451 1/20 0.42
SI P14410 1/20 0.42
MGAM2 Q2M2H8 1/20 0.42
HPGD P15428 2/20 0.42
HSD17B10 Q99714 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17424052 0.97 KDM4E (0.72) KDM4EHTTMAPK1KMT2AMEN1
SCHEMBL141536 0.92 KDM4E (0.67) KDM4EHTTMAPK1KMT2AMEN1
SCHEMBL8539269 0.92 KDM4E (0.67) KDM4EHTTMAPK1KMT2AMEN1
SCHEMBL11704831 0.87 KDM4E (0.60) KDM4EHTTMAPK1KMT2AMEN1
SCHEMBL276027 0.87 KDM4E (0.62) KDM4EHTTMAPK1KMT2AMEN1
SCHEMBL9139377 0.87 KDM4E (0.62) KDM4EHTTMAPK1KMT2AMEN1
SCHEMBL31734137 0.87 KDM4E (0.62) KDM4EHTTMAPK1KMT2AMEN1
SCHEMBL28563425 0.85 KDM4E (0.60) KDM4EHTTMAPK1KMT2AMEN1
SCHEMBL9706937 0.84 KDM4E (0.59) KDM4EHTTMAPK1KMT2AMEN1
SCHEMBL11864751 0.83 KDM4E (0.58) KDM4EHTTMAPK1KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5486556-A HEAT RESISTANT AND PHOTOSTABILITY FOR POLYMERS SANKYO COMPANY, LIMITED (JP) 1996-01-23 US disclosed
US-5446144-A Heat and light resistance SANKYO COMPANY, LIMITED (JP) 1995-08-29 US disclosed
EP-0314472-B1 Novel piperidyl-triazine derivatives and their use as polymer stabilizers SANKYO CO (JP) 1994-06-22 EP disclosed
EP-0314472-A2 Novel piperidyl-triazine derivatives and their use as polymer stabilizers Sankyo Company Limited (JP) 1989-05-03 EP disclosed
US-4443531-A S-TRIAZINE COMPOUND MITSUBISHI PAPER MILLS, LTD. (JP) 1984-04-17 US disclosed