Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 3/20 | 0.41 |
| ▸ | LPAR5 | Q9H1C0 | 3/20 | 0.41 |
| ▸ | PTGES | O14684 | 1/20 | 0.38 |
| ▸ | CCR1 | P32246 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9095979 | 0.98 | LPAR1 (0.41) | LPAR1LPAR5PTGESCCR1 | |
| SCHEMBL9094877 | 0.97 | LPAR1 (0.39) | LPAR1LPAR5 | |
| SCHEMBL9094047 | 0.97 | LPAR1 (0.39) | LPAR1LPAR5 | |
| SCHEMBL9092949 | 0.97 | LPAR1 (0.40) | LPAR1LPAR5CCR1 | |
| SCHEMBL9094116 | 0.97 | LPAR1 (0.40) | LPAR1LPAR5CCR1 | |
| SCHEMBL9094041 | 0.96 | LPAR1 (0.42) | LPAR1LPAR5 | |
| SCHEMBL9094261 | 0.96 | LPAR1 (0.42) | LPAR1LPAR5 | |
| SCHEMBL9093986 | 0.95 | LPAR1 (0.39) | LPAR1LPAR5 | |
| SCHEMBL9096364 | 0.95 | LPAR1 (0.39) | LPAR1LPAR5 | |
| SCHEMBL9094345 | 0.95 | LPAR1 (0.38) | LPAR1LPAR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996034850-A1 | CYCLOBUTANE DERIVATIVES AND THEIR USE AS INHIBITORS OF PROTEIN FARNESYLTRANSFERASE | ABBOTT LABORATORIES (US) | 1996-11-07 | — | — | WO | disclosed |