Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 7/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | NPC1 | O15118 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | PTPRB | P23467 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.35 |
| ▸ | OGA | O60502 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20586403 | 1.00 | ABCB1 (0.44) | ABCB1RAB9AMAPTNPC1ALDH1A1 | |
| SCHEMBL22045464 | 1.00 | ABCB1 (0.44) | ABCB1RAB9AMAPTNPC1ALDH1A1 | |
| SCHEMBL12902792 | 1.00 | ABCB1 (0.44) | ABCB1RAB9AMAPTNPC1ALDH1A1 | |
| SCHEMBL20529469 | 1.00 | ABCB1 (0.44) | ABCB1RAB9AMAPTNPC1ALDH1A1 | |
| SCHEMBL22045465 | 1.00 | ABCB1 (0.44) | ABCB1RAB9AMAPTNPC1ALDH1A1 | |
| SCHEMBL22852593 | 0.92 | ABCB1 (0.43) | ABCB1RAB9AMAPTNPC1ALDH1A1 | |
| SCHEMBL17728802 | 0.90 | ABCB1 (0.35) | ABCB1PTPRBMAOA | |
| SCHEMBL17728801 | 0.90 | ABCB1 (0.35) | ABCB1PTPRBMAOA | |
| SCHEMBL17728803 | 0.90 | ABCB1 (0.35) | ABCB1PTPRBMAOA | |
| SCHEMBL31232627 | 0.90 | ABCB1 (0.35) | ABCB1PTPRBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8476451-B2 | Tubulysin D analogues | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2013-07-02 | — | — | US | disclosed |
| US-20110021568-A1 | TUBULYSIN D ANALOGUES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2011-01-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110021568-A1 | TUBULYSIN D ANALOGUES | TEK, NGLY1, TEKT1 | ABCB1 2393/4885RAB9A 3085/4885MAPT 4220/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.