Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 7/20 | 0.54 |
| ▸ | MEN1 | O00255 | 6/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.54 |
| ▸ | MAPT | P10636 | 6/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | NQO2 | P16083 | 2/20 | 0.49 |
| ▸ | NQO1 | P15559 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | RECQL | P46063 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.44 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9097468 | 1.00 | NPSR1 (0.54) | NPSR1MEN1KMT2AMAPTLMNA | |
| SCHEMBL9096703 | 0.87 | MAPT (0.55) | NPSR1MEN1KMT2AMAPTLMNA | |
| SCHEMBL9096699 | 0.87 | MAPT (0.55) | NPSR1MEN1KMT2AMAPTLMNA | |
| SCHEMBL9096678 | 0.86 | MEN1 (0.54) | NPSR1MEN1KMT2AMAPTLMNA | |
| SCHEMBL9094715 | 0.86 | MAPT (0.70) | NPSR1MEN1KMT2AMAPTLMNA | |
| SCHEMBL9097764 | 0.86 | MAPT (0.70) | NPSR1MEN1KMT2AMAPTLMNA | |
| SCHEMBL9096675 | 0.86 | MEN1 (0.54) | NPSR1MEN1KMT2AMAPTLMNA | |
| SCHEMBL9097760 | 0.86 | MAPT (0.70) | NPSR1MEN1KMT2AMAPTLMNA | |
| SCHEMBL9094705 | 0.86 | MAPT (0.70) | NPSR1MEN1KMT2AMAPTLMNA | |
| SCHEMBL9095326 | 0.85 | MAPT (0.53) | NPSR1MEN1KMT2AMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5574062-A | COMPOUNDS HAVE 3-ARYL AND 7-HYDROXY OR -ACYLOXY; USE TO INHIBIT 12-LIPOXYGENASE | MORINAGA MILK INDUSTRY CO., LTD. (JP) | 1996-11-12 | — | — | US | disclosed |