Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.55 |
| ▸ | MEN1 | O00255 | 6/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.55 |
| ▸ | LMNA | P02545 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | RECQL | P46063 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | EGFR | P00533 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9098046 | 1.00 | MAPT (0.55) | MAPTMEN1KMT2ANPSR1LMNA | |
| SCHEMBL9095326 | 0.86 | MAPT (0.53) | MAPTMEN1KMT2ANPSR1LMNA | |
| SCHEMBL9095321 | 0.86 | MAPT (0.53) | MAPTMEN1KMT2ANPSR1LMNA | |
| SCHEMBL9096692 | 0.85 | MAPT (0.60) | MAPTMEN1KMT2ANPSR1LMNA | |
| SCHEMBL9096686 | 0.85 | MAPT (0.60) | MAPTMEN1KMT2ANPSR1LMNA | |
| SCHEMBL9096699 | 0.85 | MAPT (0.55) | MAPTMEN1KMT2ANPSR1LMNA | |
| SCHEMBL9096703 | 0.85 | MAPT (0.55) | MAPTMEN1KMT2ANPSR1LMNA | |
| SCHEMBL11822398 | 0.83 | MAPT (0.55) | MAPTMEN1KMT2ANPSR1LMNA | |
| SCHEMBL8107381 | 0.80 | MAPT (0.48) | MAPTMEN1KMT2ANPSR1LMNA | |
| SCHEMBL8118206 | 0.80 | MAPT (0.48) | MAPTMEN1KMT2ANPSR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5574062-A | COMPOUNDS HAVE 3-ARYL AND 7-HYDROXY OR -ACYLOXY; USE TO INHIBIT 12-LIPOXYGENASE | MORINAGA MILK INDUSTRY CO., LTD. (JP) | 1996-11-12 | — | — | US | disclosed |