Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY4R | P50391 | 11/20 | 0.48 |
| ▸ | NPY1R | P25929 | 6/20 | 0.48 |
| ▸ | NPY2R | P49146 | 4/20 | 0.48 |
| ▸ | NPY5R | Q15761 | 4/20 | 0.48 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.41 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.41 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.41 |
| ▸ | GSR | P00390 | 1/20 | 0.39 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.39 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.39 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9098515 | 1.00 | NPY4R (0.48) | NPY4RNPY1RNPY2RNPY5RGNAI3 | |
| SCHEMBL29375065 | 0.95 | NPY4R (0.44) | NPY4RNPY1RNPY2RNPY5RGNAI3 | |
| SCHEMBL30438407 | 0.94 | NPY4R (0.49) | NPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL30438367 | 0.94 | NPY4R (0.49) | NPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL18626147 | 0.94 | NPY4R (0.49) | NPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL30438004 | 0.94 | NPY4R (0.49) | NPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL30390626 | 0.94 | NPY4R (0.49) | NPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL29889403 | 0.94 | NPY4R (0.49) | NPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL30438037 | 0.94 | NPY4R (0.49) | NPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL29947047 | 0.94 | NPY4R (0.49) | NPY4RNPY1RNPY2RNPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0724447-A1 | DERIVATIZED OLIGONUCLEOTIDES HAVING IMPROVED UPTAKE AND OTHER PROPERTIES | ISIS PHARMACEUTICALS, INC. (US) | 1996-08-07 | — | — | EP | disclosed |
| EP-0724447-A4 | DERIVATIZED OLIGONUCLEOTIDES HAVING IMPROVED UPTAKE AND OTHER PROPERTIES | ISIS PHARMACEUTICALS INC (US) | 1996-01-22 | — | — | EP | disclosed |
| WO-1993007883-A1 | DERIVATIZED OLIGONUCLEOTIDES HAVING IMPROVED UPTAKE AND OTHER PROPERTIES | ISIS PHARMACEUTICALS, INC. (US) | 1993-04-29 | — | — | WO | disclosed |