Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9098249 | 0.73 | EHMT2 (0.45) | HDAC8 | |
| SCHEMBL3351144 | 0.61 | — | — | |
| SCHEMBL1162452 | 0.61 | — | — | |
| SCHEMBL1762942 | 0.61 | — | — | |
| SCHEMBL1273648 | 0.61 | — | — | |
| SCHEMBL450299 | 0.61 | — | — | |
| Hydrochloric Acid SCHEMBL6843504 | 0.59 | HDAC8 (0.43) | HDAC8 | |
| Hydrochloric Acid SCHEMBL6079983 | 0.59 | HDAC8 (0.43) | HDAC8 | |
| Ammonia Solution, Strong SCHEMBL27549784 | 0.59 | — | — | |
| SCHEMBL9629251 | 0.59 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996030370-A2 | THIAZOLE AND THIADIAZOLE DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS USEFUL IN THE TREATMENT OF THROMBOCYTOPENIA | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-10-03 | — | — | WO | disclosed |