SCHEMBL9099227

SCHEMBL9099227

CC(C)(C)C1CCC(c2cc([N+](=O)[O-])ccc2S(=O)(=O)O)CC1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSP90AA1 P07900 1/20 0.46
NT5E P21589 2/20 0.40
CHRNB4 P30926 2/20 0.38
CHRNA3 P32297 2/20 0.38
ALDH1A1 P00352 5/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
LMNA P02545 1/20 0.38
HIF1A Q16665 2/20 0.37
CYP2C19 P33261 2/20 0.37
TSHR P16473 1/20 0.37
NOS3 P29474 1/20 0.36
NOS1 P29475 1/20 0.36
NOS2 P35228 1/20 0.36
HSD11B1 P28845 1/20 0.36
SLC18A3 Q16572 1/20 0.36
AR P10275 1/20 0.35
CYP3A4 P08684 2/20 0.35
PDE2A O00408 1/20 0.35
PDE5A O76074 1/20 0.35
ALOX15 P16050 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9099242 1.00 HSP90AA1 (0.46) HSP90AA1NT5ECHRNB4CHRNA3ALDH1A1
SCHEMBL9098055 0.91 HSP90AA1 (0.54) HSP90AA1NT5ECHRNB4CHRNA3ALDH1A1
SCHEMBL9097312 0.84 HSP90AA1 (0.65) HSP90AA1NT5ECHRNB4CHRNA3ALDH1A1
SCHEMBL9097323 0.84 HSP90AA1 (0.65) HSP90AA1NT5ECHRNB4CHRNA3ALDH1A1
SCHEMBL9100934 0.80 HSP90AA1 (0.52) HSP90AA1NT5ECHRNB4CHRNA3ALDH1A1
SCHEMBL9099567 0.80 SCN9A (0.38) ALDH1A1CYP2C19HSD11B1CYP3A4L3MBTL1
SCHEMBL18952921 0.77 CHRNB4 (0.50) HSP90AA1NT5ECHRNB4CHRNA3ALDH1A1
SCHEMBL20576027 0.77 HSP90AA1 (0.43) HSP90AA1NT5ECHRNB4CHRNA3ALDH1A1
SCHEMBL20576024 0.77 HSP90AA1 (0.43) HSP90AA1NT5ECHRNB4CHRNA3ALDH1A1
SCHEMBL18952923 0.77 CHRNB4 (0.50) HSP90AA1NT5ECHRNB4CHRNA3ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5489501-A MIXTURES OF TWO COORDINATION COMPOUNDS WHICH REACT TO FORM NEW COORDINATION COMPOUND WHILE CAUSING VISIBLE COLOR CHANGES RICOH COMPANY, LTD. (JP) 1996-02-06 US disclosed
US-5446011-A Imagewise coloring when heating; mixture of n-substituted indole, aromatic polyhydroxy compound, carbonyl compound and an acid RICOH COMPANY, LTD. (JP) 1995-08-29 US disclosed