Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 4/20 | 0.64 |
| ▸ | MEN1 | O00255 | 12/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 12/20 | 0.60 |
| ▸ | MAPT | P10636 | 3/20 | 0.60 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.60 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.60 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.60 |
| ▸ | MYC | P01106 | 8/20 | 0.57 |
| ▸ | MAX | P61244 | 4/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14933669 | 0.82 | IDO1 (0.70) | IDO1MEN1KMT2AMAPTPSMD14 | |
| SCHEMBL300424 | 0.79 | IDO1 (1.00) | IDO1MEN1KMT2AMAPTPSMD14 | |
| SCHEMBL17927389 | 0.78 | IDO1 (0.67) | IDO1MEN1KMT2AMAPTPSMD14 | |
| SCHEMBL300460 | 0.77 | KMT2A (0.73) | IDO1MEN1KMT2AMAPTPSMD14 | |
| SCHEMBL6834736 | 0.76 | IDO1 (0.76) | IDO1MEN1KMT2AMAPTPSMD14 | |
| SCHEMBL6834810 | 0.75 | IDO1 (0.78) | IDO1MEN1KMT2AMAPTPSMD14 | |
| SCHEMBL6831350 | 0.75 | MEN1 (0.73) | IDO1MEN1KMT2AMAPTPSMD14 | |
| SCHEMBL6833753 | 0.74 | IDO1 (0.76) | IDO1MEN1KMT2AMAPTPSMD14 | |
| SCHEMBL3702011 | 0.74 | IDO1 (0.76) | IDO1MEN1KMT2AMAPTPSMD14 | |
| SCHEMBL3705483 | 0.74 | MEN1 (0.74) | IDO1MEN1KMT2AMAPTPSMD14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993003382-A2 | CHARACTERIZATION OF SPECIFIC DRUG RECEPTORS WITH FLUORESCENT LIGANDS | PHARMACEUTICAL DISCOVERY CORPORATION (US) | 1993-02-18 | — | — | WO | claimed |
| US-5576436-A | FLUORESCENT LABELED LIGANDS FOR MEASUREMENT OF RECEPTORS | PHARMACEUTICAL DISCOVERY CORPORATION (US) | 1996-11-19 | — | — | US | disclosed |