Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 16/20 | 0.64 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.60 |
| ▸ | PDE4A | P27815 | 2/20 | 0.60 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.60 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.60 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6654240 | 0.89 | PDE4B (0.61) | PDE4BPDE4DPDE4APDE4CPDE3B | |
| SCHEMBL6654325 | 0.89 | PDE4B (0.61) | PDE4BPDE4DPDE4APDE4CPDE3B | |
| SCHEMBL6656013 | 0.89 | PDE4B (0.61) | PDE4BPDE4DPDE4APDE4CPDE3B | |
| SCHEMBL6654148 | 0.88 | PDE4B (0.59) | PDE4BPDE4DPDE4APDE4CPDE3B | |
| SCHEMBL6654145 | 0.88 | PDE4B (0.59) | PDE4BPDE4DPDE4APDE4CPDE3B | |
| SCHEMBL6658933 | 0.88 | PDE4B (0.59) | PDE4BPDE4DPDE4APDE4CPDE3B | |
| SCHEMBL6655380 | 0.87 | PDE4B (0.61) | PDE4BPDE4DPDE4APDE4CPDE3B | |
| SCHEMBL6678792 | 0.87 | PDE4B (0.58) | PDE4BPDE4DPDE4APDE4CPDE3B | |
| SCHEMBL6660998 | 0.87 | PDE4B (0.58) | PDE4BPDE4DPDE4APDE4CPDE3B | |
| SCHEMBL6656328 | 0.86 | PDE4B (0.68) | PDE4BPDE4DPDE4APDE4CPDE3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0738715-A2 | Arylalkyl-pyridazinones | MERCK PATENT GmbH (DE) | 1996-10-23 | — | — | EP | disclosed |