Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 17/20 | 0.77 |
| ▸ | ATM | Q13315 | 3/20 | 0.77 |
| ▸ | ALDH1A1 | P00352 | 15/20 | 0.61 |
| ▸ | HPGD | P15428 | 5/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | GAA | P10253 | 5/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | GLA | P06280 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | CASP1 | P29466 | 1/20 | 0.50 |
| ▸ | CASP7 | P55210 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7897290 | 1.00 | KDM4E (0.77) | KDM4EATMALDH1A1HPGDHSD17B10 | |
| SCHEMBL21392831 | 0.84 | KDM4E (0.70) | KDM4EATMALDH1A1HPGDHSD17B10 | |
| SCHEMBL24594132 | 0.80 | SMN1; SMN2 (0.75) | KDM4EATMALDH1A1HPGDHSD17B10 | |
| SCHEMBL7581412 | 0.80 | SMN1; SMN2 (0.54) | KDM4EATMALDH1A1HPGDKMT2A | |
| SCHEMBL30487008 | 0.80 | KDM4E (0.69) | KDM4EATMALDH1A1HPGDHSD17B10 | |
| SCHEMBL14413343 | 0.80 | KDM4E (0.69) | KDM4EATMALDH1A1HPGDHSD17B10 | |
| SCHEMBL13088436 | 0.80 | KDM4E (0.69) | KDM4EATMALDH1A1HPGDHSD17B10 | |
| SCHEMBL558695 | 0.78 | KDM4E (0.68) | KDM4EATMALDH1A1HPGDHSD17B10 | |
| SCHEMBL4253087 | 0.77 | KDM4E (0.70) | KDM4EATMALDH1A1HPGDHSD17B10 | |
| SCHEMBL265369 | 0.76 | MEN1 (0.59) | KDM4EATMALDH1A1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5494949-A | SILANIZING INORGANIC OXIDES FOR COVALENT BONDING TO POLYESTER; FILLERS, REDUCTION OF VOIDS IN FILMS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1996-02-27 | — | — | US | disclosed |