Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 8/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | RARA | P10276 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | MTOR | P42345 | 1/20 | 0.62 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.48 |
| ▸ | THRA | P10827 | 4/20 | 0.47 |
| ▸ | THRB | P10828 | 4/20 | 0.47 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9670352 | 0.98 | RARB (0.61) | RARBALDH1A1MEN1KMT2ARARA | |
| SCHEMBL5328858 | 0.92 | RARB (0.59) | RARBALDH1A1MEN1KMT2ARARA | |
| SCHEMBL28873230 | 0.90 | RARB (0.72) | RARBALDH1A1MEN1KMT2ARARA | |
| SCHEMBL30053056 | 0.90 | RARB (0.72) | RARBALDH1A1MEN1KMT2ARARA | |
| SCHEMBL9472454 | 0.90 | RARB (0.72) | RARBALDH1A1MEN1KMT2ARARA | |
| SCHEMBL15583704 | 0.90 | RARB (0.72) | RARBALDH1A1MEN1KMT2ARARA | |
| SCHEMBL371605 | 0.88 | RARB (0.71) | RARBALDH1A1MEN1KMT2ARARA | |
| SCHEMBL2402134 | 0.84 | HDAC1 (0.68) | RARBALDH1A1MEN1KMT2ARARA | |
| SCHEMBL2743520 | 0.84 | HDAC1 (0.68) | RARBALDH1A1MEN1KMT2ARARA | |
| SCHEMBL5539425 | 0.84 | HDAC1 (0.54) | RARBALDH1A1MEN1KMT2ARARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102026637-B | Lipoprotein lipase-activating compositions comprising benzene derivates | OTSUKA PHARMA CO LTD | 2012-12-12 | — | — | CN | disclosed |
| CN-102026637-A | Lipoprotein lipase-activating compositions comprising benzene derivates | OTSUKA PHARMA CO LTD | 2011-04-20 | — | — | CN | disclosed |
| EP-0323441-B1 | 5-Fluorouracil derivatives | OTSUKA PHARMA CO LTD (JP) | 1996-04-24 | — | — | EP | disclosed |
| EP-0436902-B1 | 5-Fluorouracil derivatives | OTSUKA PHARMA CO LTD (JP) | 1995-06-28 | — | — | EP | disclosed |
| EP-0436902-A1 | 5-Fluorouracil derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1991-07-17 | — | — | EP | disclosed |
| US-4983609-A | Anticancer agents | OTSUKA PHARMACEUTICAL (JP) | 1991-01-08 | — | — | US | disclosed |
| US-4864021-A | ANTICARCINOGENIC AGENTS, ANTITUMOR AGENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1989-09-05 | — | — | US | disclosed |
| EP-0323441-A2 | 5-Fluorouracil derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1989-07-05 | — | — | EP | disclosed |
| EP-0180897-A2 | 5-Fluorouracil derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1986-05-14 | — | — | EP | disclosed |