SCHEMBL91009

SCHEMBL91009

O=Cc1cc2ccccc2o1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 3/20 1.00
RAB9A P51151 4/20 0.49
NPC1 O15118 2/20 0.49
MAPK1 P28482 2/20 0.49
MAPT P10636 1/20 0.49
MEN1 O00255 2/20 0.49
KMT2A Q03164 2/20 0.49
FLT3 P36888 1/20 0.48
APP P05067 1/20 0.47
TYR P14679 1/20 0.47
DAO P14920 1/20 0.47
AKR1B1 P15121 1/20 0.47
HPGD P15428 1/20 0.47
POLB P06746 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
PIM1 P11309 1/20 0.46
CA2 P00918 2/20 0.46
MAOB P27338 4/20 0.44
KDM4E B2RXH2 3/20 0.44
ALDH1A1 P00352 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9956377 1.00 CYP2A6 (1.00) CYP2A6RAB9ANPC1MAPK1MAPT
SCHEMBL29502957 1.00 CYP2A6 (1.00) CYP2A6RAB9ANPC1MAPK1MAPT
Acetaldehyde SCHEMBL6272809 0.94 CYP2A6 (0.89) CYP2A6RAB9ANPC1MAPK1MAPT
Benzofuran SCHEMBL5030477 0.88 CYP2A6 (0.77) CYP2A6RAB9ANPC1MAPK1MAPT
SCHEMBL28487808 0.85 CYP2A6 (0.72) CYP2A6RAB9ANPC1MAPK1MAPT
SCHEMBL8038555 0.80 CYP2A6 (0.67) CYP2A6RAB9ANPC1MAPK1MAPT
SCHEMBL8038562 0.80 CYP2A6 (0.67) CYP2A6RAB9ANPC1MAPK1MAPT
SCHEMBL27757855 0.79 CYP2A6 (0.62) CYP2A6RAB9ANPC1MAPK1MAPT
SCHEMBL17185672 0.78 CYP2A6 (0.64) CYP2A6RAB9ANPC1MAPK1MAPT
SCHEMBL225144 0.78 CYP2A6 (0.64) CYP2A6RAB9ANPC1MAPK1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1821 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250280857-A1 DEGRADATION-RESISTANT ALDEHYDE-CONTAINING COMPOSITIONS ZOOMESSENCE INC (US) 2025-09-11 US claimed
CN-119136683-A Degradation resistant aldehyde-containing compositions 祖姆森斯有限公司 2024-12-13 CN claimed
CN-118684596-A 2-Imine-3-carbonyl-propionamide compound, and preparation method and application thereof 上海大学 2024-09-24 CN claimed
CN-117700310-A Synthesis method of aromatic aldehyde compound or deuterated aromatic aldehyde compound 五邑大学 2024-03-15 CN claimed
CN-117362162-A Preparation method of carbonyl compound 中国科学院大连化学物理研究所 2024-01-09 CN claimed
WO-2023215706-A1 DEGRADATION-RESISTANT ALDEHYDE-CONTAINING COMPOSITIONS ZoomEssence, Inc. (US) 2023-11-09 WO claimed
CN-113735769-B Quinolinone alkaloid derivative containing acylhydrazone structure at 3-position and preparation method and application thereof 太原理工大学 2023-02-28 CN claimed
CN-115125552-B Synthesis method of tertiary phosphine compound 江苏欣诺科催化剂股份有限公司 2022-11-22 CN claimed
CN-115125552-A Synthesis method of tertiary phosphine compound 江苏欣诺科催化剂股份有限公司 2022-09-30 CN claimed
US-11427596-B2 Metal-free solvent-free synthesis of fused-pyrido heterocycles and biomedical applications Indian Institute of Technology Indore (IN) 2022-08-30 US claimed
WO-2001019796-A1 COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS AS CATHEPSIN S INHIBITORS AXYS PHARMACEUTICALS, INC. (US) 2001-03-22 WO claimed
WO-2001000594-A1 TRIAZOLE COMPOUNDS AND COMBINATORIAL LIBRARIES THEREOF LION BIOSCIENCE AG (DE) 2001-01-04 WO claimed
EP-0957093-A2 Retrovial protease inhibitors MONSANTO COMPANY (US) 1999-11-17 EP claimed
US-5643924-A Retroviral protease inhibitors MONSANTO COMPANY OF ST. LOUIS (US) 1997-07-01 US claimed
EP-0641325-A1 RETROVIRAL PROTEASE INHIBITORS MONSANTO COMPANY (US) 1995-03-08 EP claimed
WO-1993023379-A1 RETROVIRAL PROTEASE INHIBITORS MONSANTO COMPANY (US) 1993-11-25 WO claimed
US-4380629-A Styryl-like compounds showing a color-developing and bleaching behavior with improved stability and prolonged lifetime MATSUSHITA ELECTRIC INDUSTRIAL COMPANY, LIMITED (JP) 1983-04-19 US claimed
US-4314058-A Indolins styryl-like compounds MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1982-02-02 US claimed
EP-0007824-B1 BENZOFURANE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THERAPEUTIC COMPOSITION CONTAINING THEM. LABORATOIRES JACQUES LOGEAIS Société dite: (FR) 1981-07-22 EP claimed
US-4147862-A Method of preparing styryl-like compounds MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1979-04-03 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11427596-B2 Metal-free solvent-free synthesis of fused-pyrido heterocycles and biomedical applications SLC11A2, WEE1, BRCA1 CYP2A6 2848/4885RAB9A 2878/4885NPC1 4616/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.