Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.34 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.33 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.32 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.32 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.31 |
| ▸ | LTA4H | P09960 | 1/20 | 0.31 |
| ▸ | MME | P08473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9101296 | 1.00 | MEN1 (0.35) | MEN1KMT2ATSHRTAS1R3TAS1R1 | |
| SCHEMBL8894673 | 0.79 | SMN1; SMN2 (0.42) | TSHRSMN1; SMN2SLC7A5SLC1A1CA14 | |
| SCHEMBL2231422 | 0.78 | SLC7A5 (0.58) | SLC7A5SLC1A1GRIK1GRIK2 | |
| SCHEMBL9102865 | 0.78 | SLC7A5 (0.58) | SLC7A5SLC1A1GRIK1GRIK2 | |
| SCHEMBL76796 | 0.77 | SLC7A5 (0.56) | TAS1R3TAS1R1SMN1; SMN2SLC7A5CA14 | |
| SCHEMBL29783468 | 0.77 | SLC7A5 (0.56) | TAS1R3TAS1R1SMN1; SMN2SLC7A5CA14 | |
| SCHEMBL700933 | 0.77 | SLC7A5 (0.56) | TAS1R3TAS1R1SMN1; SMN2SLC7A5CA14 | |
| SCHEMBL196338 | 0.77 | SLC7A5 (0.56) | TAS1R3TAS1R1SMN1; SMN2SLC7A5CA14 | |
| Hydrochloric Acid SCHEMBL353346 | 0.75 | SLC7A5 (0.54) | TAS1R3TAS1R1SMN1; SMN2SLC7A5CA14 | |
| SCHEMBL6933793 | 0.75 | SMN1; SMN2 (0.38) | SMN1; SMN2SLC7A5SLC1A1CA14MME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5502036-A | VIRICIDES | BIOMEGA BOEHRINGER INGELHEIM RESEARCH INC. (CA) | 1996-03-26 | — | — | US | disclosed |
| EP-0411334-A1 | Antiherpes pentapeptide derivatives having a substituted aspartic acid side chain | BIO-MEGA/BOEHRINGER INGELHEIM RESEARCH INC. (CA) | 1991-02-06 | — | — | EP | disclosed |