2-Oxoisovalerate

2-Oxoisovalerate

SCHEMBL910133

CC(C)C(=O)C(=O)O.CC(C)O

nearest known ligand 0.47

Full drug profile on Sugi Atlas →

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.44
ALDH1A1 P00352 1/20 0.40
LMNA P02545 1/20 0.40
TSHR P16473 2/20 0.32
SLC7A5 Q01650 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
2-Oxoisovalerate SCHEMBL30552298 0.93
2-Oxoisovalerate SCHEMBL1462512 0.93 TP53 (0.41) TP53TSHRSLC7A5
2-Oxoisovalerate SCHEMBL42329 0.93
2-Oxoisovalerate SCHEMBL31691736 0.90
2-Oxoisovalerate SCHEMBL32667358 0.90 TP53 (0.39) TP53TSHRSLC7A5
2-Oxoisovalerate SCHEMBL468254 0.90
2-Oxoisovalerate SCHEMBL7647463 0.90
2-Oxoisovalerate SCHEMBL6846904 0.90
2-Oxoisovalerate SCHEMBL7277489 0.90
2-Oxoisovalerate SCHEMBL3782996 0.90

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9487602-B2 Furan based resin, process for the preparation thereof, and use of the compound DSM IP ASSETS B.V. (NL) 2016-11-08 US claimed
US-20130109822-A1 FURAN BASED RESIN, PROCESS FOR THE PREPARATION THEREOF, AND USE OF THE COMPOUND DSM IP ASSETS B.V. (NL) 2013-05-02 US claimed
US-20110306735-A1 PROCESS FOR THE PREPARATION OF A HYDROXY-AROMATIC RESIN; HYDROXY-AROMATIC RESIN, AND MODIFICATION THEREOF DSM IP ASSETS B.V. (NL) 2011-12-15 US claimed
US-20110021740-A1 FURAN BASED RESIN, PROCESS FOR THE PREPARATION THEREOF, AND USE OF THE COMPOUND DSM IP ASSETS B.V. (NL) 2011-01-27 US claimed
EP-2222656-A1 FURAN BASED RESIN, PROCESS FOR THE PREPARATION THEREOF, AND USE OF THE COMPOUND DSM IP Assets B.V. (NL) 2010-09-01 EP claimed
US-20090203851-A1 Process for the Preparation of a Hydroxy-Aromatic Resin: Hydroxy-Aromatic Resin, and Modification Thereof DSM IP ASSETS B.V. (NL) 2009-08-13 US claimed
WO-2009077587-A1 FURAN BASED RESIN, PROCESS FOR THE PREPARATION THEREOF, AND USE OF THE COMPOUND DSM IP ASSETS B.V. (NL) 2009-06-25 WO claimed
EP-2024317-A2 PROCESS FOR THE PREPARATION OF A HYDROXY-AROMATIC RESIN; HYDROXY-AROMATIC RESIN, AND MODIFICATION THEREOF DSMIP Assets B.V. (NL) 2009-02-18 EP claimed
WO-2007140941-A2 PROCESS FOR THE PREPARATION OF A HYDROXY-AROMATIC RESIN; HYDROXY-AROMATIC RESIN, AND MODIFICATION THEREOF DSM IP ASSETS B.V. (NL) 2007-12-13 WO claimed
US-9487602-B2 Furan based resin, process for the preparation thereof, and use of the compound DSM IP ASSETS B.V. (NL) 2016-11-08 US disclosed
US-20130109822-A1 FURAN BASED RESIN, PROCESS FOR THE PREPARATION THEREOF, AND USE OF THE COMPOUND DSM IP ASSETS B.V. (NL) 2013-05-02 US disclosed
US-20110306735-A1 PROCESS FOR THE PREPARATION OF A HYDROXY-AROMATIC RESIN; HYDROXY-AROMATIC RESIN, AND MODIFICATION THEREOF DSM IP ASSETS B.V. (NL) 2011-12-15 US disclosed
US-20110112260-A1 COMPOSITION COMPRISING A BLEND OF RESINS DSM IP ASSETS B.V. (NL) 2011-05-12 US disclosed
US-20110086988-A1 COMPOSITION COMPRISING POLYOLS EVONIK DEGUSSA GMBH (DE) 2011-04-14 US disclosed
WO-2006059903-A1 HYDROXY-AROMATIC COMPOUND, PROCESS FOR THE PREPARATION THEREOF, AND USE OF THE COMPOUND DSM IP ASSETS B.V. (NL) 2006-06-08 WO disclosed
EP-1633472-A1 ENCAPSULATED MATERIALS DSM IP Assets B.V. (NL) 2006-03-15 EP disclosed
US-20050176916-A1 Nitrogen-containing compound, the preparation thereof and application in amino-aldehyde resins DSM I.P. ASSETS B.V. (NL) 2005-08-11 US disclosed
EP-1507770-A2 NITROGEN-CONTAINING COMPOUND, THE PREPARATION THEREOF AND APPLICATION IN AMINO-ALDEHYDE RESINS DSM IP Assets B.V. (NL) 2005-02-23 EP disclosed
WO-2004110614-A1 ENCAPSULATED MATERIALS DSM IP ASSETS B.V. (NL) 2004-12-23 WO disclosed
WO-2003101973-A2 NITROGEN-CONTAINING COMPOUND, THE PREPARATION THEREOF AND APPLICATION IN AMINO-ALDEHYDE RESINS DSM IP ASSETS B.V. (NL) 2003-12-11 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090203851-A1 Process for the Preparation of a Hydroxy-Aromatic Resin: Hydroxy-Aromatic Resin, and Modification Thereof HRH3, HRH1, C9 TP53 3777/4885ALDH1A1 131/4885LMNA 1092/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.