Biphenyl

Biphenyl

SCHEMBL9102032

O=C(O)c1ccc(C(=O)O)c(C(=O)O)c1.O=C(O)c1ccc(C(=O)O)c(C(=O)O)c1.c1ccc(-c2ccccc2)cc1

nearest known ligand 0.69

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.69
CDC25B P30305 2/20 0.66
HSD17B10 Q99714 2/20 0.66
CDC25A P30304 1/20 0.66
ATM Q13315 1/20 0.60
KMO O15229 1/20 0.59
HNF4A P41235 2/20 0.55
ACMSD Q8TDX5 2/20 0.55
POLB P06746 2/20 0.53
TDP1 Q9NUW8 2/20 0.53
L3MBTL1 Q9Y468 1/20 0.53
EGFR P00533 1/20 0.53
ALDH1A1 P00352 3/20 0.53
MAPT P10636 1/20 0.53
DCLRE1A Q6PJP8 1/20 0.53
DCLRE1B Q9H816 1/20 0.53
ALOX15 P16050 1/20 0.52
MCL1 Q07820 2/20 0.50
DHFR P00374 1/20 0.50
RAB9A P51151 2/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tannin Pyrogallol SCHEMBL28918548 0.98 KDM4E (0.67) KDM4ECDC25BHSD17B10CDC25AATM
Phthalic Acid SCHEMBL20678581 0.91 CDC25B (0.77) KDM4ECDC25BHSD17B10CDC25AATM
Benzene SCHEMBL9407020 0.91 KDM4E (0.73) KDM4ECDC25BHSD17B10CDC25APOLB
SCHEMBL29899307 0.89 KDM4E (0.69) KDM4ECDC25BHSD17B10CDC25APOLB
SCHEMBL30163040 0.89 KDM4E (0.69) KDM4ECDC25BHSD17B10CDC25APOLB
SCHEMBL29350135 0.89 KDM4E (0.69) KDM4ECDC25BHSD17B10CDC25APOLB
SCHEMBL23861 0.89 KDM4E (0.69) KDM4ECDC25BHSD17B10CDC25APOLB
SCHEMBL23279 0.89 KDM4E (0.69) KDM4ECDC25BHSD17B10CDC25APOLB
SCHEMBL8180385 0.87 KDM4E (0.67) KDM4ECDC25BHSD17B10CDC25APOLB
SCHEMBL2702926 0.87 KDM4E (0.67) KDM4ECDC25BHSD17B10CDC25APOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0553612-B1 Polyimides, thermosetting resin compositions containing the polyimides, formed articles of the resin compositions, and production process of the polyimides HITACHI CHEMICAL CO LTD (JP) 1996-08-21 EP disclosed
US-5510425-A AROMATIC POLYIMIDE-EPOXY COPOLYMER MODIFIED BY BISMALEIMIDE COMPOUND; FLEXIBILITY, PEELING STRENGTH; COLDSETTING RESINS, ADHESIVES HITACHI CHEMICAL COMPANY, LTD. (JP) 1996-04-23 US disclosed
US-5508357-A SOLUBILITY IN SOLVENT, LOW MELTING POINT HITACHI CHEMICAL COMPANY, LTD. (JP) 1996-04-16 US disclosed
EP-0553612-A2 Polyimides, thermosetting resin compositions containing the polyimides, formed articles of the resin compositions, and production process of the polyimides HITACHI CHEMICAL CO., LTD. (JP) 1993-08-04 EP disclosed