SCHEMBL9102034

SCHEMBL9102034

CCc1ccccc1C(=O)N(NC(=O)c1cccc(OC)c1CC)C(C)(C)C

nearest known ligand 0.73

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ABCB1 P08183 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5062538 0.94 ABCB1 (0.55) ABCB1
SCHEMBL8998994 0.90 ABCB1 (0.58) ABCB1
SCHEMBL5056902 0.88 ABCB1 (0.69) ABCB1
SCHEMBL5057222 0.88 ABCB1 (0.49) ABCB1
SCHEMBL4040782 0.88 ABCB1 (0.56) ABCB1
SCHEMBL9103405 0.87 ABCB1 (0.64) ABCB1
SCHEMBL5053907 0.87 ABCB1 (0.50) ABCB1
SCHEMBL5134344 0.86 ABCB1 (0.48) ABCB1
SCHEMBL5057023 0.86 ABCB1 (0.48) ABCB1
SCHEMBL5053859 0.86 ABCB1 (0.52) ABCB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2460786-A1 Bioavailable diacylhydrazine ligands for modulating the expression of exogenous genes via an ecdysone receptor complex Intrexon Corporation (US) 2012-06-06 EP disclosed