SCHEMBL9102298

SCHEMBL9102298

CCC(N1c2ccccc2Sc2cc(Cl)ccc21)S(=O)(=O)O

nearest known ligand 0.48

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
SNCA P37840 1/20 0.47
BCHE P06276 3/20 0.43
ACHE P22303 3/20 0.43
RAD52 P43351 2/20 0.42
KDM4E B2RXH2 2/20 0.42
USP2 O75604 1/20 0.42
TP53 P04637 1/20 0.42
CYP3A4 P08684 1/20 0.42
MAPT P10636 1/20 0.42
ALOX15 P16050 1/20 0.42
MAPK1 P28482 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
KIF11 P52732 1/20 0.42
CYP2D6 P10635 1/20 0.42
ALDH1A1 P00352 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9104801 0.93 RAD52 (0.47) BCHEACHERAD52KDM4EUSP2
SCHEMBL6276192 0.88 BCHE (0.47) BCHEACHEMAPTCYP2D6
SCHEMBL9102414 0.86 BCHE (0.41) BCHEACHECYP3A4MAPTCYP2D6
SCHEMBL9100285 0.85 BCHE (0.42) SNCABCHEACHEMAPTL3MBTL1
SCHEMBL9102602 0.85 CYP2D6 (0.41) BCHEACHEMAPTMAPK1L3MBTL1
SCHEMBL9104535 0.83 BCHE (0.38) BCHEACHEMAPTCYP2D6
SCHEMBL9104147 0.81 BCHE (0.41) BCHEACHECYP3A4MAPTCYP2D6
SCHEMBL9105686 0.81 MAPT (0.38) BCHEACHEMAPTMAPK1CYP2D6
SCHEMBL9102726 0.81 BCHE (0.39) BCHEACHEMAPTCYP2D6
SCHEMBL9100134 0.81 CYP2D6 (0.46) BCHEACHEMAPTMAPK1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8192948-B1 Chemifluorescent substrate for peroxide and peroxidase detection PIERCE BIOTECHNOLOGY, INC. (US) 2012-06-05 US disclosed
EP-0361470-B1 Method for the chemiluminescence assay of the activity of peroxidase FUJIREBIO KK (JP) 1993-12-22 EP disclosed
US-5171668-A Measuring light emitted from contacting (iso)luminol, peroxide, peroxidase activity enhancer, such as indoanilines, phenolindophenol and N-methylphenothiazine, with labeled peroxidase antibody-antigen complex FUJIREBIO INC. (JP) 1992-12-15 US disclosed
EP-0361470-A2 Method for the chemiluminescence assay of the activity of peroxidase FUJIREBIO INC. (JP) 1990-04-04 EP disclosed