Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CB | P42338 | 14/20 | 0.48 |
| ▸ | PIK3CA | P42336 | 8/20 | 0.43 |
| ▸ | PIK3CD | O00329 | 6/20 | 0.43 |
| ▸ | PIK3CG | P48736 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MTOR | P42345 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | PIK3R1 | P27986 | 2/20 | 0.37 |
| ▸ | PIK3C2B | O00750 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5897638 | 0.89 | PIK3CB (0.64) | PIK3CBPIK3CAPIK3CDPIK3CGPIK3R1 | |
| SCHEMBL5897752 | 0.79 | PIK3CB (0.60) | PIK3CBPIK3CAPIK3CDPIK3CGPIK3R1 | |
| SCHEMBL2959231 | 0.76 | PIK3CB (0.71) | PIK3CBPIK3CAPIK3CDPIK3CGMTOR | |
| SCHEMBL373171 | 0.75 | PIK3CB (0.79) | PIK3CBPIK3CAPIK3CDPIK3CGPIK3R1 | |
| SCHEMBL373170 | 0.74 | PIK3CB (0.57) | PIK3CBPIK3CAPIK3CDPIK3CGMTOR | |
| SCHEMBL373199 | 0.71 | PIK3CB (0.60) | PIK3CBPIK3CAPIK3CDPIK3CGMTOR | |
| SCHEMBL373149 | 0.70 | PIK3CB (0.77) | PIK3CBPIK3CAPIK3CDPIK3CGMTOR | |
| SCHEMBL373551 | 0.70 | PIK3CB (0.59) | PIK3CBPIK3CAPIK3CDPIK3CGMTOR | |
| SCHEMBL5211685 | 0.69 | PIK3CB (0.53) | PIK3CBPIK3CAPIK3CDPIK3CGMTOR | |
| SCHEMBL2956679 | 0.68 | PIK3CB (0.61) | PIK3CBPIK3CAPIK3CDPIK3CGMTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1557415-B1 | HETEROCYCLIC COMPOUNDS AND ANTITUMOR DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | ZENYAKU KOGYO KK (JP) | 2012-06-06 | — | — | EP | disclosed |