Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 5/20 | 0.71 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.46 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5058444 | 0.95 | ABCB1 (0.74) | ABCB1 | |
| SCHEMBL9237401 | 0.92 | ABCB1 (0.72) | ABCB1 | |
| SCHEMBL17416621 | 0.90 | ABCB1 (0.66) | ABCB1NPC1RAB9A | |
| SCHEMBL5056990 | 0.90 | ABCB1 (0.76) | ABCB1 | |
| SCHEMBL8998725 | 0.86 | ABCB1 (0.70) | ABCB1 | |
| SCHEMBL5062578 | 0.85 | ABCB1 (0.69) | ABCB1 | |
| SCHEMBL3380590 | 0.85 | ABCB1 (0.83) | ABCB1 | |
| SCHEMBL7701546 | 0.85 | ABCB1 (0.71) | ABCB1 | |
| SCHEMBL5057245 | 0.84 | ABCB1 (0.68) | ABCB1 | |
| SCHEMBL5053856 | 0.84 | ABCB1 (0.85) | ABCB1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2460786-A1 | Bioavailable diacylhydrazine ligands for modulating the expression of exogenous genes via an ecdysone receptor complex | Intrexon Corporation (US) | 2012-06-06 | — | — | EP | disclosed |