2,4-Dichlorophenoxyacetic Acid

2,4-Dichlorophenoxyacetic Acid

SCHEMBL910271

CC(C)COC=O.O=C(O)COc1ccc(Cl)cc1Cl

nearest known ligand 0.68

Full drug profile on Sugi Atlas →

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 3/20 0.68
TSHR P16473 1/20 0.65
SMN1; SMN2 Q16637 2/20 0.54
LMNA P02545 1/20 0.52
CYP2C19 P33261 1/20 0.50
RECQL P46063 1/20 0.50
HTT P42858 1/20 0.49
PPARD Q03181 1/20 0.49
MAPT P10636 3/20 0.49
PTGDR2 Q9Y5Y4 3/20 0.48
PTGDR Q13258 1/20 0.48
ALDH1A1 P00352 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
2,4-Dichlorophenoxyacetic Acid SCHEMBL19462973 0.84 TDP1 (0.84) TDP1TSHRSMN1; SMN2LMNACYP2C19
2,4-Dichlorophenoxyacetic Acid SCHEMBL29010269 0.83 TDP1 (0.82) TDP1TSHRSMN1; SMN2LMNACYP2C19
2,4-Dichlorophenoxyacetic Acid SCHEMBL29010254 0.83 TDP1 (0.82) TDP1TSHRSMN1; SMN2LMNACYP2C19
2,4-Dichlorophenoxyacetic Acid SCHEMBL437562 0.83 TDP1 (0.82) TDP1TSHRSMN1; SMN2LMNACYP2C19
2,4-Dichlorophenoxyacetic Acid SCHEMBL23242752 0.82 TDP1 (0.93) TDP1TSHRSMN1; SMN2LMNACYP2C19
2,4-Dichlorophenoxyacetic Acid SCHEMBL27783 0.82 TDP1 (1.00) TDP1TSHRSMN1; SMN2CYP2C19RECQL
2,4-Dichlorophenoxyacetic Acid SCHEMBL226803 0.82 TDP1 (1.00) TDP1TSHRSMN1; SMN2CYP2C19RECQL
2,4-Dichlorophenoxyacetic Acid SCHEMBL31108925 0.82 TDP1 (1.00) TDP1TSHRSMN1; SMN2CYP2C19RECQL
2,4-Dichlorophenoxyacetic Acid SCHEMBL11716042 0.82 TDP1 (1.00) TDP1TSHRSMN1; SMN2CYP2C19RECQL
2,4-Dichlorophenoxyacetic Acid SCHEMBL17911677 0.81 TDP1 (0.84) TDP1TSHRSMN1; SMN2CYP2C19RECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7867946-B2 Liquid formulation BAYER CROPSCIENCE AG (DE) 2011-01-11 US disclosed