SCHEMBL9102771

SCHEMBL9102771

COc1cccc(C(=O)N(NC(=O)c2cc(Cl)nc(Cl)c2)C(C)(C)C)c1C

nearest known ligand 0.67

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ABCB1 P08183 2/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5062707 0.92 ABCB1 (0.77) ABCB1
SCHEMBL3380590 0.87 ABCB1 (0.83) ABCB1
SCHEMBL17416600 0.85 ABCB1 (0.60) ABCB1
SCHEMBL9236387 0.83 ABCB1 (0.73) ABCB1
SCHEMBL9098408 0.83 ABCB1 (0.66) ABCB1
SCHEMBL9903567 0.82 ABCB1 (0.72) ABCB1
SCHEMBL5058460 0.81 ABCB1 (0.64) ABCB1
SCHEMBL17416628 0.81 ABCB1 (0.61) ABCB1
SCHEMBL8383526 0.81 ABCB1 (0.80) ABCB1
SCHEMBL9237401 0.80 ABCB1 (0.72) ABCB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2460786-A1 Bioavailable diacylhydrazine ligands for modulating the expression of exogenous genes via an ecdysone receptor complex Intrexon Corporation (US) 2012-06-06 EP disclosed