Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | P2RX4 | Q99571 | 4/20 | 0.32 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9103542 | 0.86 | TP53 (0.33) | PDE4BP2RX4MAPTSMN1; SMN2 | |
| SCHEMBL9102272 | 0.86 | PDE4B (0.34) | PDE4BP2RX4P2RX1MAPTSMN1; SMN2 | |
| SCHEMBL9104578 | 0.83 | FNTA (0.35) | MAPT | |
| SCHEMBL9104348 | 0.81 | P2RX4 (0.40) | P2RX4P2RX1MAPTSMN1; SMN2NPSR1 | |
| SCHEMBL9105026 | 0.81 | P2RX4 (0.32) | PDE4BP2RX4 | |
| SCHEMBL9104679 | 0.80 | TP53 (0.33) | P2RX4P2RX1 | |
| SCHEMBL9102596 | 0.79 | MEN1 (0.33) | P2RX4MAPTSMN1; SMN2 | |
| SCHEMBL9100362 | 0.79 | TP53 (0.33) | PDE4BP2RX4 | |
| SCHEMBL9104011 | 0.79 | HDAC3 (0.31) | P2RX4P2RX1MAPTSMN1; SMN2NPSR1 | |
| SCHEMBL9106589 | 0.79 | P2RX4 (0.33) | PDE4BP2RX4P2RX1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8192948-B1 | Chemifluorescent substrate for peroxide and peroxidase detection | PIERCE BIOTECHNOLOGY, INC. (US) | 2012-06-05 | — | — | US | disclosed |
| EP-0361470-B1 | Method for the chemiluminescence assay of the activity of peroxidase | FUJIREBIO KK (JP) | 1993-12-22 | — | — | EP | disclosed |
| US-5171668-A | Measuring light emitted from contacting (iso)luminol, peroxide, peroxidase activity enhancer, such as indoanilines, phenolindophenol and N-methylphenothiazine, with labeled peroxidase antibody-antigen complex | FUJIREBIO INC. (JP) | 1992-12-15 | — | — | US | disclosed |
| EP-0361470-A2 | Method for the chemiluminescence assay of the activity of peroxidase | FUJIREBIO INC. (JP) | 1990-04-04 | — | — | EP | disclosed |