Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ZAP70 | P43403 | 18/20 | 0.77 |
| ▸ | FER | P16591 | 1/20 | 0.36 |
| ▸ | SYK | P43405 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1045699 | 0.91 | ZAP70 (0.84) | ZAP70FERSYK | |
| SCHEMBL1045495 | 0.87 | ZAP70 (1.00) | ZAP70FER | |
| SCHEMBL1049310 | 0.86 | ZAP70 (0.81) | ZAP70FERSYK | |
| SCHEMBL1158040 | 0.86 | ZAP70 (0.78) | ZAP70SYK | |
| SCHEMBL9102814 | 0.85 | ZAP70 (0.72) | ZAP70FERSYK | |
| SCHEMBL1158216 | 0.85 | ZAP70 (0.79) | ZAP70FERSYK | |
| SCHEMBL1159696 | 0.84 | ZAP70 (0.78) | ZAP70FERSYK | |
| SCHEMBL1158574 | 0.84 | ZAP70 (0.77) | ZAP70FERSYK | |
| SCHEMBL6525190 | 0.84 | ZAP70 (0.77) | ZAP70FERSYK | |
| SCHEMBL1158439 | 0.83 | ZAP70 (0.76) | ZAP70FERSYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2459556-A1 | 2, 7 -NAPHTHYRIDIN- 1 -ONE DERIVATIVES AS SYK KINASE INHIBITORS | IRM LLC (BM) | 2012-06-06 | — | — | EP | claimed |