SCHEMBL9103660

SCHEMBL9103660

CCCCc1cc(CCCC)c2c(c1)Sc1ccc(CCCC)cc1N2CCCS(=O)(=O)O

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.38
ALOX15 P16050 3/20 0.38
TDP1 Q9NUW8 3/20 0.38
CYP3A4 P08684 3/20 0.38
RAD52 P43351 2/20 0.38
MAPK1 P28482 2/20 0.38
TP53 P04637 2/20 0.38
KDM4E B2RXH2 1/20 0.38
USP2 O75604 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
MEN1 O00255 4/20 0.37
KMT2A Q03164 4/20 0.37
POLB P06746 3/20 0.37
MMP13 P45452 3/20 0.37
HPGD P15428 3/20 0.34
HSD17B10 Q99714 3/20 0.34
LMNA P02545 3/20 0.34
ALOX12 P18054 2/20 0.34
CASP1 P29466 2/20 0.34
ALDH1A1 P00352 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9105617 0.93 MAPT (0.38) MAPTALOX15TDP1CYP3A4RAD52
SCHEMBL9106574 0.90 MEN1 (0.47) MAPTALOX15TDP1CYP3A4RAD52
SCHEMBL9103903 0.89 MAPT (0.41) MAPTALOX15TDP1CYP3A4RAD52
SCHEMBL9101693 0.86 MAPT (0.45) MAPTALOX15TDP1CYP3A4RAD52
SCHEMBL9101381 0.85 MAPT (0.40) MAPTALOX15TDP1CYP3A4RAD52
SCHEMBL9107653 0.84 MAPT (0.38) MAPTALOX15TDP1CYP3A4RAD52
SCHEMBL9105725 0.83 MAPT (0.53) MAPTALOX15TDP1CYP3A4RAD52
SCHEMBL9100805 0.82 MEN1 (0.48) MAPTALOX15TDP1CYP3A4RAD52
SCHEMBL9103778 0.82 MAPT (0.41) MAPTALOX15TDP1CYP3A4RAD52
SCHEMBL9100359 0.81 MAPT (0.45) MAPTALOX15TDP1CYP3A4RAD52

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8192948-B1 Chemifluorescent substrate for peroxide and peroxidase detection PIERCE BIOTECHNOLOGY, INC. (US) 2012-06-05 US disclosed
EP-0361470-B1 Method for the chemiluminescence assay of the activity of peroxidase FUJIREBIO KK (JP) 1993-12-22 EP disclosed
US-5171668-A Measuring light emitted from contacting (iso)luminol, peroxide, peroxidase activity enhancer, such as indoanilines, phenolindophenol and N-methylphenothiazine, with labeled peroxidase antibody-antigen complex FUJIREBIO INC. (JP) 1992-12-15 US disclosed
EP-0361470-A2 Method for the chemiluminescence assay of the activity of peroxidase FUJIREBIO INC. (JP) 1990-04-04 EP disclosed