Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 20/20 | 0.79 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1311772 | 0.81 | MAPK14 (1.00) | MAPK14 | |
| SCHEMBL1311125 | 0.81 | MAPK14 (0.66) | MAPK14 | |
| SCHEMBL1311225 | 0.80 | MAPK14 (1.00) | MAPK14 | |
| SCHEMBL1313572 | 0.79 | MAPK14 (0.61) | MAPK14 | |
| SCHEMBL1310604 | 0.78 | MAPK14 (1.00) | MAPK14 | |
| SCHEMBL1310858 | 0.78 | MAPK14 (0.80) | MAPK14 | |
| SCHEMBL1310738 | 0.77 | MAPK14 (0.82) | MAPK14 | |
| SCHEMBL1313213 | 0.77 | MAPK14 (1.00) | MAPK14 | |
| SCHEMBL1311179 | 0.77 | MAPK14 (0.84) | MAPK14 | |
| SCHEMBL10286418 | 0.77 | MAPK14 (0.71) | MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2334674-B1 | Pyridazino- pyridinone compounds for the treatment of protein kinase mediated diseases. | AMGEN INC (US) | 2012-06-06 | — | — | EP | disclosed |