Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX4 | Q99571 | 10/20 | 0.35 |
| ▸ | P2RX1 | P51575 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | VDR | P11473 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9106662 | 0.93 | P2RX4 (0.35) | P2RX4P2RX1MAPTALDH1A1KDM4E | |
| SCHEMBL9103982 | 0.92 | P2RX4 (0.34) | P2RX4P2RX1HDAC3HDAC6P2RX3 | |
| SCHEMBL9102665 | 0.91 | KDM4E (0.31) | MAPTALDH1A1KDM4EF2VDR | |
| SCHEMBL9102037 | 0.90 | P2RX4 (0.36) | P2RX4P2RX1SMN1; SMN2 | |
| SCHEMBL9104487 | 0.87 | P2RX4 (0.41) | P2RX4P2RX1MAPTKDM4EHDAC3 | |
| SCHEMBL9104489 | 0.87 | P2RX4 (0.43) | P2RX4P2RX1KDM4EHDAC3HDAC6 | |
| SCHEMBL9103621 | 0.86 | P2RX4 (0.43) | P2RX4P2RX1MAPTALDH1A1KDM4E | |
| SCHEMBL9103488 | 0.86 | KDM4E (0.30) | MAPTALDH1A1KDM4EF2VDR | |
| SCHEMBL9101909 | 0.85 | AHR (0.39) | P2RX4P2RX1MAPTALDH1A1KDM4E | |
| SCHEMBL9106581 | 0.85 | PIM1 (0.39) | P2RX4P2RX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9632034-B2 | Fluorogenic and chromogenic substrate | LI-COR, INC. (US) | 2017-04-25 | — | — | US | disclosed |
| US-20160266045-A1 | FLUOROGENIC AND CHROMOGENIC SUBSTRATE | LI-COR, INC. (US) | 2016-09-15 | — | — | US | disclosed |
| US-8192948-B1 | Chemifluorescent substrate for peroxide and peroxidase detection | PIERCE BIOTECHNOLOGY, INC. (US) | 2012-06-05 | — | — | US | disclosed |
| EP-0361470-B1 | Method for the chemiluminescence assay of the activity of peroxidase | FUJIREBIO KK (JP) | 1993-12-22 | — | — | EP | disclosed |
| US-5171668-A | Measuring light emitted from contacting (iso)luminol, peroxide, peroxidase activity enhancer, such as indoanilines, phenolindophenol and N-methylphenothiazine, with labeled peroxidase antibody-antigen complex | FUJIREBIO INC. (JP) | 1992-12-15 | — | — | US | disclosed |
| EP-0361470-A2 | Method for the chemiluminescence assay of the activity of peroxidase | FUJIREBIO INC. (JP) | 1990-04-04 | — | — | EP | disclosed |